Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
GALR2 [plasma membrane]
Stable Identifier
R-HSA-388949
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
RecName: Full=Galanin receptor type 2; AltName: Full=GAL2-R; AltName: Full=GALR2;
GN Name=GALR2; Synonyms=GALNR2;
OS Homo sapiens, GALR2_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
GALR1-3:GAL [plasma membrane] (Homo sapiens)
GALR1-3 [plasma membrane] (Homo sapiens)
GALR2 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
GALR1-3:GAL [plasma membrane] (Homo sapiens)
GALR1-3 [plasma membrane] (Homo sapiens)
GALR2 [plasma membrane] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
GALR1-3:GAL [plasma membrane] (Homo sapiens)
GALR1-3 [plasma membrane] (Homo sapiens)
GALR2 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
GALR1-3:GAL [plasma membrane] (Homo sapiens)
GALR1-3 [plasma membrane] (Homo sapiens)
GALR2 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
GALR1-3:GAL [plasma membrane] (Homo sapiens)
GALR1-3 [plasma membrane] (Homo sapiens)
GALR2 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
GALR1-3:GAL [plasma membrane] (Homo sapiens)
GALR1-3 [plasma membrane] (Homo sapiens)
GALR2 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Galanin receptors can bind galanin (Homo sapiens)
GALR1-3 [plasma membrane] (Homo sapiens)
GALR2 [plasma membrane] (Homo sapiens)
GALR1-3:GAL [plasma membrane] (Homo sapiens)
GALR1-3 [plasma membrane] (Homo sapiens)
GALR2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O43603 GALR2
Gene Names
GALR2, GALNR2
Chain
chain:1-387
Reference Genes
BioGPS Gene:8811 GALR2
COSMIC (genes):GALR2 GALR2
CTD Gene:8811 GALR2
dbSNP Gene:8811 GALR2
ENSEMBL:ENSG00000182687 GALR2
ENSEMBL_homo_sapiens_GENE:ENSG00000182687.4 GALR2
HGNC:4133 GALR2
KEGG Gene (Homo sapiens):8811 GALR2
Monarch:8811 GALR2
NCBI Gene:8811 GALR2
OMIM:603691 GALR2
UCSC:O43603 GALR2
Reference Transcript
RefSeq:NM_003857.3 GALR2
Other Identifiers
11731328_at
16838017
211226_PM_at
211226_at
31905_at
3735384
3735385
3735389
3735390
3735391
8010030
8811
ADDON002378.hg
A_23_P77756
GE54346
GO:0003012
GO:0004930
GO:0004966
GO:0005515
GO:0005886
GO:0005929
GO:0006351
GO:0006355
GO:0006629
GO:0006936
GO:0007165
GO:0007166
GO:0007186
GO:0007188
GO:0007189
GO:0007194
GO:0007200
GO:0007204
GO:0007218
GO:0007611
GO:0007631
GO:0016020
GO:0017046
GO:0023052
GO:0030154
GO:0031175
GO:0042923
GO:0043226
GO:0043647
GO:0045944
GO:0046488
GO:0048856
GO:0050877
GO:0055085
GO:0060089
GO:0090663
GO:1902608
HMNXSV003042994
ILMN_1733847
PH_hs_0009600
TC17000864.hg
g4165080_3p_at
Participates
as a member of
GALR1-3 [plasma membrane] (Homo sapiens)
Inferred To
GALR2 [plasma membrane]
(Bos taurus)
GALR2 [plasma membrane]
(Canis familiaris)
GALR2 [plasma membrane]
(Gallus gallus)
GALR2 [plasma membrane]
(Sus scrofa)
Galr2 [plasma membrane]
(Mus musculus)
Galr2 [plasma membrane]
(Rattus norvegicus)
galr2a [plasma membrane]
(Danio rerio)
Cross References
RefSeq
NP_003848.1
Guide to Pharmacology - Targets
244
OpenTargets
ENSG00000182687
ZINC - Substances
GALR2_HUMAN
HPA
ENSG00000182687-GALR2
GeneCards
O43603
ZINC target
O43603
Ensembl
ENSG00000182687
,
ENSP00000329684
,
ENST00000329003
PRO
O43603
Pharos - Targets
O43603
ZINC - Predictions - Purchasable
GALR2_HUMAN
PDB
7XJL
,
7XBD
,
7XJK
,
7WQ4
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text