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PDGFB(1-81) [Golgi lumen]
Stable Identifier
R-HSA-389058
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
Cleaved fragment of PDGF B-chain
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by PDGF (Homo sapiens)
PDGF-AB clevage by Furin (Homo sapiens)
Cleaved PDGF-B peptides [Golgi lumen] (Homo sapiens)
PDGFB(1-81) [Golgi lumen] (Homo sapiens)
PDGF-BB clevage by Furin (Homo sapiens)
Cleaved PDGF-B peptides [Golgi lumen] (Homo sapiens)
PDGFB(1-81) [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P01127 PDGFB
Gene Names
PDGFB, PDGF2, SIS
Chain
signal peptide:1-20, propeptide:21-81, chain:82-190, propeptide:191-241
Reference Genes
BioGPS Gene:5155 PDGFB
COSMIC (genes):PDGFB PDGFB
CTD Gene:5155 PDGFB
dbSNP Gene:5155 PDGFB
ENSEMBL:ENSG00000100311 PDGFB
HGNC:8800 PDGFB
KEGG Gene (Homo sapiens):5155 PDGFB
Monarch:5155 PDGFB
NCBI Gene:5155 PDGFB
OMIM:190040 PDGFB
UCSC:P01127 PDGFB
Reference Transcript
RefSeq:NM_002608.3 PDGFB
RefSeq:NM_033016.3 PDGFB
Other Identifiers
0006620368
0006840026
11731665_a_at
11731666_at
11731667_s_at
1573_at
16935228
204200_s_at
216061_x_at
217112_at
3961066
3961067
3961069
3961070
3961071
3961072
3961076
3961077
3961080
3961084
3961087
3961088
3961089
3961090
5155
8076195
A_24_P339944
GE60436
GO:0000003
GO:0000139
GO:0000165
GO:0000278
GO:0001892
GO:0001938
GO:0002376
GO:0002548
GO:0002576
GO:0003013
GO:0003104
GO:0003674
GO:0005161
GO:0005515
GO:0005518
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005737
GO:0005783
GO:0005788
GO:0005794
GO:0005796
GO:0005886
GO:0005975
GO:0006259
GO:0006464
GO:0006468
GO:0006629
GO:0006810
GO:0006950
GO:0007049
GO:0007165
GO:0007267
GO:0007275
GO:0007507
GO:0008083
GO:0008150
GO:0008283
GO:0008284
GO:0009058
GO:0009611
GO:0009790
GO:0009986
GO:0010512
GO:0010544
GO:0010628
GO:0010629
GO:0014068
GO:0014911
GO:0016020
GO:0016176
GO:0016192
GO:0016323
GO:0018105
GO:0018108
GO:0030154
GO:0030198
GO:0030234
GO:0030335
GO:0031012
GO:0031093
GO:0031410
GO:0031954
GO:0032091
GO:0032147
GO:0032148
GO:0034641
GO:0035655
GO:0035793
GO:0038001
GO:0040011
GO:0042056
GO:0042802
GO:0042803
GO:0043226
GO:0043406
GO:0043410
GO:0043536
GO:0043552
GO:0044281
GO:0045737
GO:0045840
GO:0045892
GO:0045893
GO:0046982
GO:0048008
GO:0048016
GO:0048146
GO:0048407
GO:0048661
GO:0048856
GO:0048870
GO:0050731
GO:0050918
GO:0050921
GO:0051301
GO:0051781
GO:0051897
GO:0060326
GO:0061098
GO:0062023
GO:0070374
GO:0070528
GO:0070851
GO:0071363
GO:0071506
GO:0072126
GO:0072255
GO:0072593
GO:0090280
GO:0140014
GO:1900127
GO:1902894
GO:1902895
GO:1904707
GO:1904754
GO:1905064
GO:1905176
GO:2000379
GO:2000573
GO:2000591
Hs.172928.1.A1_3p_s_at
Hs.1976.2.S1_3p_at
ILMN_1737695
ILMN_1775822
ILMN_2394305
M12783_at
TC22000802.hg
X83705_s_at
g4505680_3p_a_at
Participant Of
hasMember
Cleaved PDGF-B peptides [Golgi lumen]
Other forms of this molecule
PDGFB(82-241) [platelet alpha granule lumen]
PDGFB(21-81) [platelet alpha granule lumen]
PDGFB(191-241) [Golgi lumen]
PDGFB(1-241) [Golgi membrane]
PDGFB(1-241) [endoplasmic reticulum lumen]
PDGFB(82-241) [extracellular region]
PDGFB (82-190) [extracellular region]
Inferred To
pdgfba [Golgi lumen] (Danio rerio)
PDGFB [Golgi lumen] (Canis familiaris)
PDGFB [Golgi lumen] (Gallus gallus)
Pvf1 [Golgi lumen] (Drosophila melanogaster)
Pdgfb [Golgi lumen] (Mus musculus)
Pdgfb [Golgi lumen] (Rattus norvegicus)
pvf-1 [Golgi lumen] (Caenorhabditis elegans)
pdgfb [Golgi lumen] (Xenopus tropicalis)
Cross References
RefSeq
NP_002599.1
,
NP_148937.1
OpenTargets
ENSG00000100311
HPA
ENSG00000100311-PDGFB
GeneCards
P01127
ZINC - Substances
PDGFB_HUMAN
ZINC target
P01127
Ensembl
ENSG00000100311
,
ENSP00000370963
,
ENST00000381551
,
ENST00000331163
,
ENSP00000330382
PRO
P01127
Orphanet
17757
ZINC - Predictions - Purchasable
PDGFB_HUMAN
PDB
4HQX
,
4HQU
,
1PDG
,
3MJG
,
4QCI
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P16234 PDGFRA
47
PDGFRA N659K [plasma membrane]
(R-HSA-9671535)
PDGFRA L629P [plasma membrane]
(R-HSA-9673596)
PDGFRA T674I [plasma membrane]
(R-HSA-9673603)
PDGFRA S601P [plasma membrane]
(R-HSA-9673600)
PDGFRA Y288C [endoplasmic reticulum membrane]
(R-HSA-9671971)
PDGFRA del375-455 [endoplasmic reticulum membrane]
(R-HSA-9673609)
p-11Y PDGFRA Y288C [endoplasmic reticulum membrane]
(R-HSA-9672027)
p-11Y PDGFRA del375-455 [endoplasmic reticulum membrane]
(R-HSA-9673634)
PDGFRA D842_M844del [plasma membrane]
(R-HSA-9671526)
PDGFRA D842Y [plasma membrane]
(R-HSA-9671956)
PDGFRA D842V [plasma membrane]
(R-HSA-9671549)
PDGFRA D843_846del [plasma membrane]
(R-HSA-9671537)
PDGFRA D842_H845del [plasma membrane]
(R-HSA-9671545)
PDGFRA D842del [plasma membrane]
(R-HSA-9671538)
PDGFRA D842_I843delinsV [plasma membrane]
(R-HSA-9671563)
PDGFRA D846Y [plasma membrane]
(R-HSA-9671958)
PDGFRA D843_845del [plasma membrane]
(R-HSA-9671552)
PDGFRA D842_D846del [plasma membrane]
(R-HSA-9671547)
PDGFRA N848K [plasma membrane]
(R-HSA-9671961)
PDGFRA Y849C [plasma membrane]
(R-HSA-9671974)
PDGFRA D843_844del [plasma membrane]
(R-HSA-9671559)
PDGFRA D846V [plasma membrane]
(R-HSA-9674306)
PDGFRA D842L [plasma membrane]
(R-HSA-9674303)
PDGFRA V561D [plasma membrane]
(R-HSA-9671557)
PDGFRA V561A [plasma membrane]
(R-HSA-9671968)
PDGFRA V536E [plasma membrane]
(R-HSA-9671964)
PDGFRA V536M [plasma membrane]
(R-HSA-9676950)
p-11Y PDGFRA D842V [plasma membrane]
(R-HSA-9671979)
p-11Y PDGFRA D846Y [plasma membrane]
(R-HSA-9672009)
p-11Y PDGFRA D842del [plasma membrane]
(R-HSA-9671998)
p-11Y PDGFRA D843_844del [plasma membrane]
(R-HSA-9672001)
p-11Y PDGFRA D842_I843delinsV [plasma membrane]
(R-HSA-9671991)
p-11Y PDGFRA D843_846del [plasma membrane]
(R-HSA-9672007)
p-11Y PDGFRA D842Y [plasma membrane]
(R-HSA-9671982)
p-11Y PDGFRA D842_H845del [plasma membrane]
(R-HSA-9671989)
p-11Y PDGFRA D842_D846del [plasma membrane]
(R-HSA-9671986)
p-10Y PDGFRA Y849C [plasma membrane]
(R-HSA-9671977)
p-11Y PDGFRA D843_845del [plasma membrane]
(R-HSA-9672003)
p-11Y PDGFRA N848K [plasma membrane]
(R-HSA-9672015)
p-11Y PDGFRA D842L dimer [plasma membrane]
(R-HSA-9674313)
p-11Y PDGFRA D846V [plasma membrane]
(R-HSA-9674316)
p-11Y PDGFRA V536E [plasma membrane]
(R-HSA-9672018)
p-11Y PDGFRA V536M [plasma membrane]
(R-HSA-9676956)
p-11Y PDGFRA V561D [plasma membrane]
(R-HSA-9672025)
p-11Y PDGFRA V561A [plasma membrane]
(R-HSA-9672021)
PDGFRA [plasma membrane]
(R-HSA-186794)
p-11Y-PDGFRA [plasma membrane]
(R-HSA-186806)
0.733
11
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