Reactome | SMARCE1 [nucleoplasm]

SMARCE1 [nucleoplasm]

Stable Identifier

R-HSA-389258

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

BAF57

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q969G3 SMARCE1

Gene Names

SMARCE1, BAF57

Chain

chain:1-411

Reference Genes

BioGPS Gene:6605 SMARCE1

COSMIC (genes):SMARCE1 SMARCE1

CTD Gene:6605 SMARCE1

dbSNP Gene:6605 SMARCE1

ENSEMBL:ENSG00000073584 SMARCE1

HGNC:11109 SMARCE1

KEGG:hsa:6605 SMARCE1

Monarch:6605 SMARCE1

NCBI Gene:6605 SMARCE1

OMIM:603111 SMARCE1

UCSC:Q969G3 SMARCE1

Reference Transcript

RefSeq:NM_003079.4 SMARCE1

Participates

as a component of

as an input of

as a candidate of

SWI/SNF additional components [nucleoplasm] (Homo sapiens)

Inferred To

smarce1 [nucleoplasm] (Xenopus tropicalis)

swsn-3 [nucleoplasm] (Caenorhabditis elegans)

Ghost homologue of SMARCE1 [nucleoplasm] (Saccharomyces cerevisiae)

Ghost homologue of SMARCE1 [nucleoplasm] (Schizosaccharomyces pombe)

SMARCE1 [nucleoplasm] (Bos taurus)

SMARCE1 [nucleoplasm] (Canis familiaris)

SMARCE1 [nucleoplasm] (Dictyostelium discoideum)

SMARCE1 [nucleoplasm] (Gallus gallus)

SMARCE1 [nucleoplasm] (Sus scrofa)

Bap111 [nucleoplasm] (Drosophila melanogaster)

Smarce1 [nucleoplasm] (Mus musculus)

Smarce1 [nucleoplasm] (Rattus norvegicus)

Cross References

OpenTargets

ENSG00000073584

ENSEMBL

ENSP00000464511, ENSP00000392958, ENSP00000466608, ENST00000447024, ENSP00000496445, ENST00000578044, ENST00000377808, ENSP00000411607, ENSG00000073584, ENST00000400122, ENSP00000323967, ENSP00000496094, ENSP00000367039, ENST00000348513, ENST00000643683, ENSP00000496097, ENSP00000494771, ENST00000643318, ENST00000264640, ENST00000647508, ENST00000644701

GeneCards

SMARCE1

HPA

ENSG00000073584-SMARCE1

PRO

Q969G3

Pharos - Targets

Q969G3

GlyGen

Q969G3

Orphanet

SMARCE1

PDB

7VDV, 7CYU, 6LTH, 7Y8R, 6LTJ

Interactors (95)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q12824 SMARCB1	1	SMARCB1 [nucleoplasm] (R-HSA-389261)	0.848	15
UniProt:O14497 ARID1A	1	ARID1A [nucleoplasm] (R-HSA-389259)	0.788	8
UniProt:P51532 SMARCA4	1	SMARCA4 [nucleoplasm] (R-HSA-201686)	0.788	8
UniProt:Q96GM5 SMARCD1	1	SMARCD1 [nucleoplasm] (R-HSA-389255)	0.788	9
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.781	7
UniProt:Q68CP9 ARID2	1	ARID2 [nucleoplasm] (R-HSA-5225613)	0.748	7
UniProt:Q92922 SMARCC1	1	SMARCC1 [nucleoplasm] (R-HSA-389257)	0.725	6
UniProt:Q8TAQ2 SMARCC2	1	SMARCC2 [nucleoplasm] (R-HSA-389263)	0.725	6
UniProt:Q8NFD5 ARID1B	1	ARID1B [nucleoplasm] (R-HSA-5225635)	0.725	6
UniProt:Q6STE5 SMARCD3	1	SMARCD3 [nucleoplasm] (R-HSA-400141)	0.725	5
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.718	6
UniProt:Q6A162 KRT40	1	KRT40 [cytosol] (R-HSA-6809605)	0.718	6
UniProt:Q9BYV2 TRI54			0.718	6
UniProt:Q8TD10 MIPO1			0.718	6
UniProt:Q01850 CDR2			0.718	6
UniProt:Q15323 KRT31	1	KRT31 [cytosol] (R-HSA-6809616)	0.718	6
UniProt:Q15311 RALBP1	1	RALBP1 [cytosol] (R-HSA-195194)	0.718	6
UniProt:Q8NHQ1 CEP70	1	CEP70 [cytosol] (R-HSA-380257)	0.718	6
UniProt:O96019 ACTL6A	1	ACTL6A [nucleoplasm] (R-HSA-2980912)	0.669	3
UniProt:P0C7W6 CC172			0.666	4
UniProt:Q9BVG8 KIFC3			0.666	4
UniProt:Q96MT8 CEP63	1	CEP63 [cytosol] (R-HSA-380267)	0.666	4
UniProt:Q9HCU9 BRMS1	1	BRMS1 [nucleoplasm] (R-HSA-4650034)	0.646	3
UniProt:Q92925 SMARCD2	1	SMARCD2 [nucleoplasm] (R-HSA-5225626)	0.643	5
UniProt:P51531 SMARCA2	1	SMARCA2 [nucleoplasm] (R-HSA-389256)	0.643	5
UniProt:Q8WUB8 PHF10	1	PHF10 [nucleoplasm] (R-HSA-9932814)	0.643	5
UniProt:Q4VC05 BCL7A	1	BCL7A [nucleoplasm] (R-HSA-9727449)	0.643	4
UniProt:Q15532 SS18	1	SS18 [nucleoplasm] (R-HSA-9727441)	0.643	3
UniProt:Q92785 DPF2	1	DPF2 [nucleoplasm] (R-HSA-9727509)	0.643	4
UniProt:Q92782 DPF1	1	DPF1 [nucleoplasm] (R-HSA-8855001)	0.643	4
UniProt:Q86U86 PBRM1	1	PBRM1 [nucleoplasm] (R-HSA-389254)	0.643	4
UniProt:Q9NPI1 BRD7	1	BRD7 [nucleoplasm] (R-HSA-3222092)	0.643	4
UniProt:Q3LI67 KRTAP6-3	1	KRTAP6-3 [cytosol] (R-HSA-6810281)	0.556	3
UniProt:Q92764 KRT35	1	KRT35 [cytosol] (R-HSA-6809595)	0.556	3
UniProt:Q15642-2 TRIP10			0.556	6
UniProt:Q8TD31-3 CCHCR1			0.556	3
UniProt:Q12929 EPS8	1	EPS8 [cytosol] (R-HSA-9662382)	0.556	3
UniProt:Q96HT8 MR1L1			0.556	3
UniProt:Q9BXU0 TEX12	1	TEX12 [nucleoplasm] (R-HSA-912441)	0.556	3
UniProt:Q8WYH8 ING5	1	ING5 [nucleoplasm] (R-HSA-3215169)	0.556	3
UniProt:Q96LB3-2 IFT74			0.556	3
UniProt:Q96MT8-3 CEP63			0.556	3
UniProt:P37198 NUP62	2	NUP62 [nuclear envelope] (R-HSA-157713) NUP62 [cytosol] (R-HSA-9634226)	0.556	3
UniProt:P08779 KRT16	1	KRT16 [cytosol] (R-HSA-201581)	0.556	3
UniProt:Q96R06 SPAG5			0.556	3
UniProt:Q7Z3Y8 KRT27	1	KRT27 [cytosol] (R-HSA-6809587)	0.556	3
UniProt:Q8N0S2 SYCE1	1	SYCE1 [nucleoplasm] (R-HSA-912456)	0.556	3
UniProt:Q6NUQ1 RINT1	1	RINT1 [cytosol] (R-HSA-6810991)	0.556	3
UniProt:Q5JR59-3 MTUS2			0.556	3
UniProt:Q07627 KRTAP1-1	1	KRTAP1-1 [cytosol] (R-HSA-6809855)	0.556	3
IntAct:EBI-10204964 285622			0.556	3
UniProt:G5E9W6 G5E9W6			0.556	3
UniProt:Q9NRI5-2 DISC1			0.556	3
UniProt:Q9Y2J4 AMOTL2	1	AMOTL2 [cytosol] (R-HSA-2028606)	0.556	3
UniProt:Q15642 TRIP10	1	TRIP10 [cytosol] (R-HSA-195120)	0.556	3
UniProt:Q96A65-2 Q96A652			0.556	3
UniProt:Q4V328 GRAP1			0.556	3
UniProt:A8MQ03 CRTP1			0.556	3
UniProt:O75558 STX11			0.556	3
UniProt:Q96L14 C170L			0.556	3
UniProt:P02533 KRT14	1	KRT14 [cytosol] (R-HSA-446091)	0.556	3
UniProt:Q8N1B4 VPS52	1	VPS52 [trans-Golgi network membrane] (R-HSA-6811029)	0.556	3
UniProt:A1L4K1 FSD2			0.556	3
UniProt:Q8N6Y0 USBP1			0.556	3
UniProt:Q96AA8 JKIP2			0.556	3
UniProt:O76011 KRT34	1	KRT34 [cytosol] (R-HSA-6809608)	0.556	3
UniProt:Q96JN2-2 CCDC136			0.556	3
UniProt:P60410 KRTAP10-8	1	KRTAP10-8 [cytosol] (R-HSA-6810301)	0.556	3
UniProt:P40222 TXLNA	1	TXLNA [cytosol] (R-HSA-449124)	0.556	3
UniProt:P60411 KRTAP10-9	1	KRTAP10-9 [cytosol] (R-HSA-6810277)	0.556	3
UniProt:Q9Y2J4-4 AMOTL2			0.556	3
UniProt:Q9NTX9 F217B			0.556	3
UniProt:Q6FHY5 Q6FHY5			0.556	3
IntAct:EBI-16435328 CCSB ORF ID			0.556	3
UniProt:Q5JR59 MTUS2			0.556	3
UniProt:O76014 KRT37	1	KRT37 [cytosol] (R-HSA-6809614)	0.556	3
UniProt:Q6A163 KRT39	1	KRT39 [cytosol] (R-HSA-6809592)	0.556	3
UniProt:Q9NPJ6 MED4	1	MED4 [nucleoplasm] (R-HSA-350263)	0.556	3
UniProt:Q13099 IFT88	8	PolyUb-Misfolded IFT88 [lysosomal lumen] (R-HSA-9660026) PolyUb-Misfolded IFT88 [cytosol] (R-HSA-9641125) Ub-Misfolded IFT88 [cytosol] (R-HSA-9641114) Misfolded IFT88 [cytosol] (R-HSA-9640115) Misfolded IFT88 [cilium] (R-HSA-9640106) IFT88 [cilium] (R-HSA-5610385) PolyUb-Misfolded IFT88 [late endosome lumen] (R-HSA-9660031) IFT88 [ciliary tip] (R-HSA-5625371)	0.556	3
UniProt:Q7Z3S9 NOTCH2NLA	3	NOTCH2NLA [extracellular region] (R-HSA-9908935) NOTCH2NLA(1-?) [extracellular region] (R-HSA-9911493) NOTCH2NLA(?-236) [extracellular region] (R-HSA-9911490)	0.556	3
UniProt:P62333 PSMC6	2	PSMC6 [cytosol] (R-HSA-68783) PSMC6 [nucleoplasm] (R-HSA-174319)	0.556	3
UniProt:Q9UPT5 EXOC7	2	EXOC7 [plasma membrane] (R-HSA-2872288) EXOC7 [cytosol] (R-HSA-5623386)	0.556	5
UniProt:P08727 KRT19	1	KRT19 [cytosol] (R-HSA-6809617)	0.556	3
UniProt:O43482 OIP5	1	OIP5 [nucleoplasm] (R-HSA-606286)	0.556	3
UniProt:P50222 MEOX2			0.556	3
UniProt:P19012 KRT15	1	KRT15 [cytosol] (R-HSA-6809589)	0.556	3
UniProt:A6NEM1 GG6L9			0.556	3
UniProt:O75177 SS18L1	1	SS18L1 [nucleoplasm] (R-HSA-9727481)	0.527	2
UniProt:Q92769 HDAC2	2	HDAC2 [nucleoplasm] (R-HSA-205135) monoSUMO1-K462-HDAC2 [nucleoplasm] (R-HSA-4615958)	0.527	2
UniProt:Q8WUZ0 BCL7C	1	BCL7C [nucleoplasm] (R-HSA-9727457)	0.527	4
UniProt:Q92784 DPF3	1	DPF3 [nucleoplasm] (R-HSA-9727469)	0.527	3
UniProt:Q13547 HDAC1	2	HDAC1 [nucleoplasm] (R-HSA-205021) monoSUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030)	0.527	2
UniProt:P11308 ERG			0.519	2
UniProt:P01100 FOS	2	FOS [nucleoplasm] (R-HSA-450216) p-T325,T331,S362,S374-FOS [nucleoplasm] (R-HSA-450283)	0.483	2
UniProt:P05412 JUN	4	JUN [nucleoplasm] (R-HSA-450250) p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [cytosol] (R-HSA-168194) p-S63,S73-JUN [cytosol] (R-HSA-8868682)	0.462	2

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