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QRFP [extracellular region]
Stable Identifier
R-HSA-389399
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Neuropeptide QRFP, RecName: Full=Orexigenic neuropeptide QRFP; AltName: Full=P518; Contains: RecName: Full=QRF-amide; AltName: Full=Pyroglutamylated arginine-phenylalanine-amide peptide; AltName: Full=Neuropeptide RF-amide; Flags: Precursor;
GN Name=QRFP;
OS Homo sapiens, OX26_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
QRFPR:QRFP [plasma membrane] (Homo sapiens)
QRFP [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
QRFPR:QRFP [plasma membrane] (Homo sapiens)
QRFP [extracellular region] (Homo sapiens)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
QRFPR:QRFP [plasma membrane] (Homo sapiens)
QRFP [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
QRFPR:QRFP [plasma membrane] (Homo sapiens)
QRFP [extracellular region] (Homo sapiens)
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
QRFPR:QRFP [plasma membrane] (Homo sapiens)
QRFP [extracellular region] (Homo sapiens)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Homo sapiens)
QRFP [extracellular region] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Orexin and neuropeptides FF and QRFP bind to their respective receptors (Homo sapiens)
The orphan QRFP receptor can bind neuropeptide QRFP (Homo sapiens)
QRFP [extracellular region] (Homo sapiens)
QRFPR:QRFP [plasma membrane] (Homo sapiens)
QRFP [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P83859 QRFP
Gene Names
QRFP
Chain
signal peptide:1-18, propeptide:19-90, peptide:91-133
Reference Genes
BioGPS Gene:347148 QRFP
COSMIC (genes):QRFP QRFP
CTD Gene:347148 QRFP
dbSNP Gene:347148 QRFP
ENSEMBL:ENSG00000188710 QRFP
HGNC:29982 QRFP
KEGG Gene (Homo sapiens):347148 QRFP
Monarch:347148 QRFP
NCBI Gene:347148 QRFP
OMIM:609795 QRFP
UCSC:P83859 QRFP
Reference Transcript
RefSeq:NM_198180.2 QRFP
Other Identifiers
0000380603
11734463_at
17099148
3227453
3227455
3227459
3227461
3227462
347148
8164630
A_33_P3272080
A_33_P3383601
GO:0003013
GO:0003674
GO:0005184
GO:0005575
GO:0005576
GO:0007165
GO:0007186
GO:0007218
GO:0007625
GO:0007626
GO:0008150
GO:0031854
GO:0045777
GO:0060259
ILMN_1718848
PH_hs_0037645
TC09001659.hg
Participant Of
input
The orphan QRFP receptor can bind neuropeptide QRFP
hasMember
Ligands of GPCRs that activate Gq/11 [extracellular region]
hasComponent
QRFPR:QRFP [plasma membrane]
Inferred To
QRFP [extracellular region] (Canis familiaris)
QRFP [extracellular region] (Gallus gallus)
QRFP [extracellular region] (Sus scrofa)
Qrfp [extracellular region] (Mus musculus)
Qrfp [extracellular region] (Rattus norvegicus)
qrfp [extracellular region] (Xenopus tropicalis)
Cross References
RefSeq
NP_937823.1
OpenTargets
ENSG00000188710
HPA
ENSG00000188710-QRFP
GeneCards
P83859
Ensembl
ENST00000623824
,
ENSG00000188710
,
ENSP00000485512
,
ENST00000343079
,
ENSP00000345487
PRO
P83859
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