phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate

Stable Identifier
R-HSA-389622
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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VLCS (very long chain acyl-CoA synthetase), associated with the inner surface of the peroxisomal membrane, cayalyzes the reaction of phytanate, CoA-SH, and ATP to form phytanoyl-CoA, AMP, and pyrophosphate (Steinberg et al. 1999).

Literature References
PubMed ID Title Journal Year
10198260 Human very-long-chain acyl-CoA synthetase: cloning, topography, and relevance to branched-chain fatty acid metabolism

Steinberg, SJ, Wang, SJ, Kim, DG, Mihalik, SJ, Watkins, PA

Biochem Biophys Res Commun 1999
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
phytanate-CoA ligase activity of SLC27A2 [peroxisomal membrane]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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