Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA

Stable Identifier
R-HSA-389897
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Peroxisomal 2-methylacyl-CoA racemase (AMACR) catalyzes the isomerization of (2R)-pristanoyl-CoA to form (2S)-pristanoyl-CoA. The active form of the enzyme is a monomer (Schmitz et al. 1995; Amery et al. 2000; Ferdinandusse et al. 2000).

Literature References
PubMed ID Title Journal Year
11060359 Subcellular localization and physiological role of alpha-methylacyl-CoA racemase

Ferdinandusse, S, Denis, S, IJlst, L, Dacremont, G, Waterham, HR, Wanders, RJ

J Lipid Res 2000
11060344 Mitochondrial and peroxisomal targeting of 2-methylacyl-CoA racemase in humans

Amery, L, Fransen, M, De Nys, K, Mannaerts, GP, Van Veldhoven, PP

J Lipid Res 2000
7649182 Purification and characterization of an alpha-methylacyl-CoA racemase from human liver

Schmitz, W, Albers, C, Fingerhut, R, Conzelmann, E

Eur J Biochem 1995
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
alpha-methylacyl-CoA racemase activity of AMACR [peroxisomal matrix]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created
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