Grb2 binds pBTLA

Stable Identifier
R-HSA-389919
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
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The sequence around Y226 in the BTLA cytoplasmic domain is a predicted recruitment site for Grb2. Despite the prediction there is no direct evidence of protein recruitment to this tyrosine motif.

Literature References
PubMed ID Title Journal Year
16932752 Balancing co-stimulation and inhibition with BTLA and HVEM

Murphy, KM, Nelson, CA, Sedý, JR

Nat Rev Immunol 2006
12796776 BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1

Watanabe, N, Gavrieli, M, Sedý, JR, Yang, J, Fallarino, F, Loftin, SK, Hurchla, MA, Zimmerman, N, Sim, J, Zang, X, Murphy, TL, Russell, JH, Allison, JP, Murphy, KM

Nat Immunol 2003
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created