SUMOylation of EP300 with SUMO1

Stable Identifier
R-HSA-3899291
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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EP300 (p300) is SUMOylated at lysine-1020 and lysine-1024 with SUMO1 (Girdwood et al. 2003). SUMOylation of EP300 alleviates transcriptional repression caused by the CRD1 domain.

Literature References
PubMed ID Title Journal Year
12718889 P300 transcriptional repression is mediated by SUMO modification

Girdwood, D, Bumpass, D, Vaughan, OA, Thain, A, Anderson, LA, Snowden, AW, Garcia-Wilson, E, Perkins, ND, Hay, RT

Mol. Cell 2003
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
SUMO transferase activity of SUMO1:C93-UBE2I [nucleoplasm]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created