In two cycles of beta-oxidation mediated by the same enzyme activities responsible for the conversion of pristanoyl-CoA to 4,8,12-trimethyltridecanoyl-CoA, the latter molecule is converted to 4,8-dimethylnonanoyl-CoA. Two molecules each of O2, H2O, NAD+, and CoASH are consumed in the process and two molecules of H2O2 and NADH + H+ are generated, together with single molecules of acetyl-CoA and propionyl-CoA (Verhoeven et al. 1998).
Verhoeven, NM, Roe, DS, Kok, RM, Wanders, RJ, Jakobs, C, Roe, CR
© 2021 Reactome