Reactome | propionyl-CoA + carnitine => propionylcarnitine + CoASH

propionyl-CoA + carnitine => propionylcarnitine + CoASH

Stable Identifier

R-HSA-390284

Type

Reaction [transition]

Species

Homo sapiens

Compartment

peroxisomal matrix

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propionyl-CoA + carnitine => propionylcarnitine + CoASH

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Peroxisomal carnitineacetyltransferase (CRAT) catalyzes the reaction of propionyl-CoA and carnitine to form propionylcarnitine and CoASH. The active form of the enzyme is a monomer (Bloisi et al. 1990; Wu et al. 2003).

Literature References

PubMed ID	Title	Journal	Year
2351134	Purification and properties of carnitine acetyltransferase from human liver Bloisi, W, Colombo, I, Garavaglia, B, Giardini, R, Finocchiaro, G, DiDonato, S	Eur J Biochem	1990
12562770	Structure of human carnitine acetyltransferase. Molecular basis for fatty acyl transfer. Wu, D, Govindasamy, L, Lian, W, Gu, Y, Kukar, T, Agbandje-McKenna, M, McKenna, R	J Biol Chem	2003