SUMOylation of PPARGC1A with SUMO1

Stable Identifier
R-HSA-3903017
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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SUMOylation of PPARGC1A with SUMO1
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As infered from mouse homologs, PPARGC1A (PGC-1alpha) is SUMOylated at lysine-184 with SUMO1. SUMOylation reduces transcription activation by PPARGC1A.
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Catalyst Activity

SUMO transferase activity of SUMO1:C93-UBE2I [nucleoplasm]

Physical Entity
SUMO1:C93-UBE2I [nucleoplasm] (Homo sapiens)
Activity
SUMO transferase activity (GO:0019789)
Inferred From
Sumoylation of Ppargc1a with Sumo1 (Mus musculus)
Authored
May, B  (2013-07-15)
Reviewed
Niskanen, E  (2018-05-09)
Niskanen, E  (2018-08-08)
Created
May, B  (2013-07-17)
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