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ADRA1A,B,D [plasma membrane]
Stable Identifier
R-HSA-390684
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Alpha-1 adrenoceptor
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (12/13) signalling events (Homo sapiens)
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Homo sapiens)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Homo sapiens)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (inactive). [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
The Ligand:GPCR:G12/13 complex dissociates (Homo sapiens)
GPCRs that activate G12/13 [plasma membrane] (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate G12/13:Heterotrimeric G-protein G12/13 (active). [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate G12/13 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
GPCRs that activate Gq/11 [plasma membrane] (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Amine ligand-binding receptors (Homo sapiens)
Adrenoceptors (Homo sapiens)
ADRA1A,B,D bind ADR,NAd (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
α1-agonists:ADRA1A,B,D [plasma membrane] (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
α1-antagonists:ADRA1A,B,D [plasma membrane] (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
α1-agonists bind ADRA1A,B,D (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
α1-agonists:ADRA1A,B,D [plasma membrane] (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
α1-antagonists bind ADRA1A,B,D (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
α1-antagonists:ADRA1A,B,D [plasma membrane] (Homo sapiens)
ADRA1A,B,D [plasma membrane] (Homo sapiens)
Participants
members
ADRA1A [plasma membrane]
(Homo sapiens)
ADRA1B [plasma membrane]
(Homo sapiens)
ADRA1D [plasma membrane]
(Homo sapiens)
Participates
as an input of
α1-antagonists bind ADRA1A,B,D (Homo sapiens)
α1-agonists bind ADRA1A,B,D (Homo sapiens)
ADRA1A,B,D bind ADR,NAd (Homo sapiens)
as a member of
GPCRs that activate Gq/11 [plasma membrane] (Homo sapiens)
GPCRs that activate G12/13 [plasma membrane] (Homo sapiens)
as a component of
α1-agonists:ADRA1A,B,D [plasma membrane] (Homo sapiens)
α1-antagonists:ADRA1A,B,D [plasma membrane] (Homo sapiens)
ADRA1A,B,D:ADR,NAd [plasma membrane] (Homo sapiens)
Inferred To
ser-5 [plasma membrane]
(Caenorhabditis elegans)
adra1bb [plasma membrane]
(Danio rerio)
ADRA1A,B,D [plasma membrane]
(Bos taurus)
ADRA1A,B,D [plasma membrane]
(Canis familiaris)
ADRA1A,B,D [plasma membrane]
(Drosophila melanogaster)
ADRA1A,B,D [plasma membrane]
(Gallus gallus)
ADRA1A,B,D [plasma membrane]
(Mus musculus)
ADRA1A,B,D [plasma membrane]
(Rattus norvegicus)
ADRA1A,B,D [plasma membrane]
(Sus scrofa)
ADRA1A,B,D [plasma membrane]
(Xenopus tropicalis)
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