Peroxisomal lipid metabolism

Stable Identifier
R-HSA-390918
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Peroxisomal lipid metabolism
Click the image above or here to open this pathway in the Pathway Browser

In humans, the catabolism of phytanate, pristanate, and very long chain fatty acids as well as the first four steps of the biosynthesis of plasmalogens are catalyzed by peroxisomal enzymes. Defects in any of these enzymes or in the assembly of peroxisomes are associated with severe developmental disorders (Wanders and Watherham 2006).

Literature References
PubMed ID Title Journal Year
16756494 Biochemistry of mammalian peroxisomes revisited

Wanders, RJ, Waterham, HR

Annu Rev Biochem 2006
Participants
Events
Participant Of
hasEvent
Event Information
Go Biological Process
fatty acid catabolic process (0009062)
Orthologous Events
Peroxisomal lipid metabolism (Bos taurus)
Peroxisomal lipid metabolism (Caenorhabditis elegans)
Peroxisomal lipid metabolism (Canis familiaris)
Peroxisomal lipid metabolism (Danio rerio)
Peroxisomal lipid metabolism (Dictyostelium discoideum)
Peroxisomal lipid metabolism (Drosophila melanogaster)
Peroxisomal lipid metabolism (Gallus gallus)
Peroxisomal lipid metabolism (Mus musculus)
Peroxisomal lipid metabolism (Plasmodium falciparum)
Peroxisomal lipid metabolism (Rattus norvegicus)
Peroxisomal lipid metabolism (Saccharomyces cerevisiae)
Peroxisomal lipid metabolism (Schizosaccharomyces pombe)
Peroxisomal lipid metabolism (Sus scrofa)
Peroxisomal lipid metabolism (Xenopus tropicalis)
Authored
D'Eustachio, P  (2009-02-11)
Reviewed
Jassal, B  (2009-02-27)
Created
D'Eustachio, P  (2009-02-11)