Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
NOP56 [cytosol]
Stable Identifier
R-HSA-391293
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
NOL5A
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Protein folding (Homo sapiens)
Chaperonin-mediated protein folding (Homo sapiens)
Association of TriC/CCT with target proteins during biosynthesis (Homo sapiens)
Association of CCT/TriC with other substrates during biosynthesis (unknown chaperone) (Homo sapiens)
CCT/TRiC:substrate complex [cytosol] (Homo sapiens)
unfolded CCT/TRiC substrate candidates [cytosol] (Homo sapiens)
NOP56 [cytosol] (Homo sapiens)
unfolded CCT/TRiC substrate candidates [cytosol] (Homo sapiens)
NOP56 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00567 NOP56
Gene Names
NOP56, NOL5A
Chain
chain:1-594
Reference Genes
BioGPS Gene:10528 NOP56
COSMIC (genes):NOP56 NOP56
CTD Gene:10528 NOP56
dbSNP Gene:10528 NOP56
ENSEMBL:ENSG00000101361 NOP56
ENSEMBL_homo_sapiens_GENE:ENSG00000101361.17 NOP56
HGNC:15911 NOP56
KEGG Gene (Homo sapiens):10528 NOP56
Monarch:10528 NOP56
NCBI Gene:10528 NOP56
OMIM:614154 NOP56
UCSC:O00567 NOP56
Reference Transcript
RefSeq:NM_006392.3 NOP56
Other Identifiers
10528
11746134_s_at
11746135_x_at
11755342_x_at
11758679_s_at
200874_PM_s_at
200874_s_at
200875_PM_s_at
200875_s_at
2947503
2947504
2947506
2947507
34882_at
3873878
3873880
3873883
3873887
3873888
3873892
3873893
3873896
3873898
3873901
3873905
3873909
3873913
3873914
3873915
A_23_P79927
A_23_P91328
GE60295
GO:0001650
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0005732
GO:0005737
GO:0006364
GO:0016020
GO:0030515
GO:0031428
GO:0032040
GO:0042254
GO:0042274
GO:0043226
GO:0045296
GO:0070761
GO:1990226
GO:1990904
HMNXSV003021207
Hs.296585.0.S1_3p_s_at
ILMN_1705407
ILMN_1787628
ILMN_2044832
PH_hs_0018286
TC20001062.hg
g5453793_3p_a_at
Participates
as a candidate of
unfolded CCT/TRiC substrate candidates [cytosol] (Homo sapiens)
Other forms of this molecule
NOP56 [nucleoplasm]
Cross References
RefSeq
NP_006383.2
OpenTargets
ENSG00000101361
HPA
ENSG00000101361-NOP56
GeneCards
O00567
Ensembl
ENST00000329276
,
ENSG00000101361
,
ENSP00000370589
PRO
O00567
Pharos - Targets
O00567
Orphanet
20398
PDB
7MQ8
,
7MQA
,
7MQ9
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y2X3 NOP58
3
polySUMO2-K467,K497-NOP58 [nucleoplasm]
(R-HSA-4570460)
monoSUMO1-K467,K497-NOP58 [nucleoplasm]
(R-HSA-4570470)
NOP58 [nucleoplasm]
(R-HSA-4570488)
0.643
3
UniProt:P01106 MYC
2
PolyUb-MYC [nucleoplasm]
(R-HSA-6783169)
MYC [nucleoplasm]
(R-HSA-188379)
0.564
2
UniProt:Q9Y4Z2 NEUROG3
1
NEUROG3 [nucleoplasm]
(R-HSA-189530)
0.527
2
UniProt:P15880 RPS2
3
RPS2 [nucleoplasm]
(R-HSA-6790655)
Me2aR-RPS2 [cytosol]
(R-HSA-8879138)
RPS2 [cytosol]
(R-HSA-72347)
0.527
2
UniProt:P06748 NPM1
11
monoSUMO1-K263-NPM1 [nucleoplasm]
(R-HSA-4086039)
polySUMO2,3-K263-NPM1 [nucleoplasm]
(R-HSA-4086056)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm]
(R-HSA-9725010)
NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730703)
NPM1(1-117)-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730697)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699861)
NPM1(1-117)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699834)
NPM1 [granular component]
(R-HSA-9017702)
NPM1 [nucleoplasm]
(R-HSA-606320)
NPM1 [cytosol]
(R-HSA-3008211)
p-S4-NPM1 [cytosol]
(R-HSA-6801679)
0.527
2
UniProt:P0DTC9 N
13
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]
(R-COV-9729325)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]
(R-COV-9729339)
N [plasma membrane]
(R-COV-9694356)
SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]
(R-COV-9756489)
N [cytosol]
(R-COV-9694300)
p-S188,206-N [cytosol]
(R-COV-9729324)
p-8S-N [cytosol]
(R-COV-9729335)
p-8S,2T-N [cytosol]
(R-COV-9729277)
p-11S,2T-N [cytosol]
(R-COV-9729264)
p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729308)
ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729275)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9729341)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729340)
0.527
3
UniProt:P62753 RPS6
4
RPS6 [nucleoplasm]
(R-HSA-6790606)
3OHR147-RPS6 [cytosol]
(R-HSA-9629876)
p-5S-RPS6 [cytosol]
(R-HSA-165727)
RPS6 [cytosol]
(R-HSA-72381)
0.483
2
UniProt:P03372 ESR1
10
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
ESR1 [nucleoplasm]
(R-HSA-446168)
ESR1 [cytosol]
(R-HSA-9020968)
0.462
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text