Eicosanoid ligand-binding receptors

Stable Identifier
R-HSA-391903
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Pathway
Species
Homo sapiens
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Eicosanoids, derived from polyunsaturated 20-carbon fatty acids, are paracrine and autocrine regulators of inflammation, smooth muscle contraction, and blood coagulation. The actions of eicosanoids are mediated by eicosanoid receptors, most of which are GPCRs. There are four types of eicosanoid GPCRs in humans; leukotriene, lipoxin (Brink C et al, 2003), prostanoid (Coleman RA et al, 1994) and oxoeicosanoid (Brink C et al, 2004) receptors.

Literature References
PubMed ID Title Journal Year
12615958 International Union of Pharmacology XXXVII. Nomenclature for leukotriene and lipoxin receptors

Brink, C, Dahlén, SE, Drazen, J, Evans, JF, Hay, DW, Nicosia, S, Serhan, CN, Shimizu, T, Yokomizo, T

Pharmacol Rev 2003
15001665 International Union of Pharmacology XLIV. Nomenclature for the oxoeicosanoid receptor

Brink, C, Dahlén, SE, Drazen, J, Evans, JF, Hay, DW, Rovati, GE, Serhan, CN, Shimizu, T, Yokomizo, T

Pharmacol Rev 2004
7938166 International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes

Coleman, RA, Smith, WL, Narumiya, S

Pharmacol Rev 1994
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