Reactome | ATP2A3 [endoplasmic reticulum membrane]

ATP2A3 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-391965

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Sarcoplasmic/endoplasmic reticulum calcium ATPase 3, AT2A3_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q93084 ATP2A3

Gene Names

ATP2A3

Chain

chain:1-999

Reference Genes

BioGPS Gene:489 Q930842

COSMIC (genes):ATP2A3 ATP2A3

CTD Gene:489 Q930842

dbSNP Gene:489 Q930842

ENSEMBL:ENSG00000074370 ATP2A3

HGNC:813 Q930842

KEGG:hsa:489 Q930842

Monarch:489 Q930842

NCBI Gene:489 Q930842

OMIM:601929 Q930842

UCSC:Q93084 Q930842

Reference Transcript

Participates

as a member of

ATP2A1-3 [endoplasmic reticulum membrane] (Homo sapiens)

Other forms of this molecule

ATP2A3 [platelet dense tubular network membrane]

Inferred To

sca-1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

atp2a3 [endoplasmic reticulum membrane] (Xenopus tropicalis)

ATP2A3 [endoplasmic reticulum membrane] (Bos taurus)

ATP2A3 [endoplasmic reticulum membrane] (Canis familiaris)

ATP2A3 [endoplasmic reticulum membrane] (Drosophila melanogaster)

ATP2A3 [endoplasmic reticulum membrane] (Gallus gallus)

ATP2A3 [endoplasmic reticulum membrane] (Mus musculus)

ATP2A3 [endoplasmic reticulum membrane] (Plasmodium falciparum)

ATP2A3 [endoplasmic reticulum membrane] (Rattus norvegicus)

ATP2A3 [endoplasmic reticulum membrane] (Sus scrofa)

Cross References

RefSeq

NP_777613.1, NP_777614.1, NP_005164.2, NP_777615.1, NP_777616.1, NP_777617.1, NP_777618.1

Guide to Pharmacology - Targets

842

OpenTargets

ENSG00000074370

ENSEMBL

ENSP00000301387, ENSP00000380229, ENST00000397041, ENST00000397035, ENST00000397043, ENSP00000380234, ENSP00000380236, ENSP00000353072, ENSP00000312577, ENST00000309890, ENST00000359983, ENST00000352011, ENSG00000074370

HPA

ENSG00000074370-ATP2A3

GeneCards

ATP2A3

PRO

Q93084

Pharos - Targets

Q93084

GlyGen

Q93084

HMDB Protein

HMDBP01255

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC5 M	10	M [plasma membrane] (R-COV-9755780) N-glycan M [virion membrane] (R-COV-9694385) M [virion membrane] (R-COV-9694320) M [endocytic vesicle membrane] (R-COV-9694563) N-glycan M [endocytic vesicle membrane] (R-COV-9694738) M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694439) N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694446) M [endoplasmic reticulum membrane] (R-COV-9767620) nascent M [endoplasmic reticulum lumen] (R-COV-9694279) N-glycan M [endoplasmic reticulum membrane] (R-COV-9694684)	0.527	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.527	7

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