Phosphorylation of L1 by CK-II

Stable Identifier
R-HSA-392752
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

CKII phosphorylates L1CAM at serine 1181, just after the AP-2 recognition site (Y1176RSLE motif). CKII-dependent phosphorylation of S1181 has been shown to regulate trafficking of the internalized L1 and subsequent axon growth.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
kinase activity of Casein kinase II [cytosol]
Physical Entity
Activity
Orthologous Events