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TUBB2A unfolded [cytosol]
Stable Identifier
R-HSA-392776
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
unfolded beta tubulin 2A
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Protein folding (Homo sapiens)
Chaperonin-mediated protein folding (Homo sapiens)
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding (Homo sapiens)
Formation of tubulin folding intermediates by CCT/TriC (Homo sapiens)
ADP is exchanged for ATP in the (ADP:CCT/TriC):tubulin complex (Homo sapiens)
CCT/TRiC:ADP:non-native tubulin [cytosol] (Homo sapiens)
Unfolded alpha/beta tubulin [cytosol] (Homo sapiens)
TUBB2A unfolded [cytosol] (Homo sapiens)
CCT/TRiC:ATP:unfolded tubulin complex [cytosol] (Homo sapiens)
Unfolded alpha/beta tubulin [cytosol] (Homo sapiens)
TUBB2A unfolded [cytosol] (Homo sapiens)
Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC (Homo sapiens)
CCT/TRiC:ATP:unfolded tubulin complex [cytosol] (Homo sapiens)
Unfolded alpha/beta tubulin [cytosol] (Homo sapiens)
TUBB2A unfolded [cytosol] (Homo sapiens)
Prefoldin mediated transfer of substrate to CCT/TriC (Homo sapiens)
Actin/tubulin:prefoldin complex associates with CCT/TriC (Homo sapiens)
Prefoldin-associated actin/tubulin [cytosol] (Homo sapiens)
unfolded actin/tubulin [cytosol] (Homo sapiens)
TUBB2A unfolded [cytosol] (Homo sapiens)
actin/tubulin-bound CCT/TRiC:ADP [cytosol] (Homo sapiens)
unfolded actin/tubulin [cytosol] (Homo sapiens)
TUBB2A unfolded [cytosol] (Homo sapiens)
unfolded actin/tubulin associates with prefoldin (Homo sapiens)
Prefoldin-associated actin/tubulin [cytosol] (Homo sapiens)
unfolded actin/tubulin [cytosol] (Homo sapiens)
TUBB2A unfolded [cytosol] (Homo sapiens)
unfolded actin/tubulin [cytosol] (Homo sapiens)
TUBB2A unfolded [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13885 TUBB2A
Gene Names
TUBB2A, TUBB2
Chain
chain:1-445
Reference Genes
BioGPS Gene:7280 TUBB2A
COSMIC (genes):TUBB2A TUBB2A
CTD Gene:7280 TUBB2A
dbSNP Gene:7280 TUBB2A
ENSEMBL:ENSG00000137267 TUBB2A
HGNC:12412 TUBB2A
KEGG Gene (Homo sapiens):7280 TUBB2A
Monarch:7280 TUBB2A
NCBI Gene:7280 TUBB2A
OMIM:615101 TUBB2A
UCSC:Q13885 TUBB2A
Reference Transcript
RefSeq:NM_001310315.1 TUBB2A
RefSeq:NM_001069.2 TUBB2A
Other Identifiers
0001190129
0001570161
11719788_s_at
11719789_x_at
17015143
202154_x_at
204141_at
209372_x_at
213476_3p_x_at
213476_x_at
2939214
2939215
2939216
2939217
2939218
2939221
2939223
2939224
2939225
2939226
2939235
2939236
2939239
2939240
2939246
2939256
296_at
297_g_at
33678_i_at
39331_at
4050505
429_f_at
471_f_at
7280
8123644
A_23_P19291
A_23_P501276
GE79068
GO:0000166
GO:0000226
GO:0000278
GO:0001764
GO:0003674
GO:0003924
GO:0005198
GO:0005200
GO:0005515
GO:0005525
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005737
GO:0005856
GO:0005874
GO:0007010
GO:0007017
GO:0007049
GO:0008150
GO:0030154
GO:0040011
GO:0043167
GO:0043226
GO:0048856
GO:0048870
GO:0070062
GO:1903561
HMNXSV003044067
HMNXSV003055194
Hs.179661.3.S1_3p_x_at
ILMN_1343292
ILMN_2038775
ILMN_2044813
PH_hs_0026825
TC06001226.hg
TC06003365.hg
TC06003368.hg
TC06003369.hg
g4507728_3p_at
Participates
as a member of
Unfolded alpha/beta tubulin [cytosol] (Homo sapiens)
unfolded actin/tubulin [cytosol] (Homo sapiens)
Other forms of this molecule
TUBB2A folding intermediate [cytosol]
Polyglycyl-TUBB2A [cytosol]
Polyglutamyl-TUBB2A [cytosol]
TUBB2A [axonemal microtubule]
TUBB2A [cytosol]
Cross References
RefSeq
NP_001297244.1
,
NP_001060.1
OpenTargets
ENSG00000137267
HPA
ENSG00000137267-TUBB2A
GeneCards
Q13885
Ensembl
ENST00000333628
,
ENSP00000369703
,
ENSG00000137267
PRO
Q13885
Pharos - Targets
Q13885
GlyGen
Q13885
Orphanet
25007
HMDB Protein
HMDBP08602
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P05412 JUN
4
JUN [nucleoplasm]
(R-HSA-450250)
p-S63,S73-JUN [nucleoplasm]
(R-HSA-450237)
JUN [cytosol]
(R-HSA-168194)
p-S63,S73-JUN [cytosol]
(R-HSA-8868682)
0.666
5
UniProt:P55212 CASP6
5
CASP6 (1-293) [cytosol]
(R-HSA-6798132)
CASP6(194-293) [nucleoplasm]
(R-HSA-352246)
CASP6(24-179) [nucleoplasm]
(R-HSA-352247)
CASP6(24-179) [cytosol]
(R-HSA-350313)
CASP6(194-293) [cytosol]
(R-HSA-266128)
0.556
3
UniProt:P04183 TK1
1
TK1 [cytosol]
(R-HSA-73500)
0.553
2
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.547
3
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