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p-Y-CRMP1 [cytosol]
Stable Identifier
R-HSA-399784
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Tyrosine phosphorylated CRMP-1
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
Semaphorin interactions (Homo sapiens)
CRMPs in Sema3A signaling (Homo sapiens)
Tyrosine phosphorylation of CRMPs by Fes (Homo sapiens)
Sema3A:NP-1:Plexin-A:Fes:CRMP [plasma membrane] (Homo sapiens)
pCRMP's tertramers (Y499) [cytosol] (Homo sapiens)
Fes phosphorylated CRMP's 1-5 [cytosol] (Homo sapiens)
p-Y-CRMP1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q14194 CRMP1
Gene Names
CRMP1, DPYSL1, ULIP3
Chain
chain:1-572
Reference Genes
BioGPS Gene:1400 CRMP1
COSMIC (genes):CRMP1 CRMP1
CTD Gene:1400 CRMP1
dbSNP Gene:1400 CRMP1
ENSEMBL:ENSG00000072832 CRMP1
ENSEMBL_homo_sapiens_GENE:ENSG00000072832.15 CRMP1
HGNC:2365 CRMP1
KEGG Gene (Homo sapiens):1400 CRMP1
Monarch:1400 CRMP1
NCBI Gene:1400 CRMP1
OMIM:602462 CRMP1
UCSC:Q14194 CRMP1
Reference Transcript
RefSeq:NM_001288662.1 CRMP1
RefSeq:NM_001014809.2 CRMP1
RefSeq:NM_001288661.1 CRMP1
RefSeq:NM_001313.4 CRMP1
Other Identifiers
11716501_a_at
11716502_x_at
11716503_a_at
11716504_x_at
1400
16973975
202517_PM_at
202517_at
2759045
2759046
2759047
2759050
2759052
2759058
2759059
2759061
2759062
2759063
2759064
2759065
2759066
2759068
2759070
2759072
2759073
2759079
2759085
2759086
2759087
2759088
2759089
2759095
2759096
40272_at
8099172
A_23_P132889
A_24_P20506
D78012_at
GE57292
GE86402
GO:0003824
GO:0005515
GO:0005737
GO:0005813
GO:0005815
GO:0005819
GO:0005829
GO:0005856
GO:0006139
GO:0007399
GO:0008092
GO:0010977
GO:0016787
GO:0016810
GO:0016812
GO:0030154
GO:0030426
GO:0030496
GO:0031005
GO:0042802
GO:0042995
GO:0043204
GO:0043226
GO:0048856
HMNXSV003027267
HMNXSV003038360
ILMN_1664502
ILMN_1789541
ILMN_1811405
PH_hs_0009357
TC04000997.hg
g4503050_3p_at
Participates
as a member of
Fes phosphorylated CRMP's 1-5 [cytosol] (Homo sapiens)
Other forms of this molecule
CRMP1 [cytosol]
p-T509,T514,S518,S522-CRMP1 [cytosol]
p-S522-CRMP1 [cytosol]
Inferred To
phospho-unc-33 [cytosol]
(Caenorhabditis elegans)
Homologues of p-Y-CRMP1 [cytosol]
(Caenorhabditis elegans)
phospho-CRMP1A [cytosol]
(Gallus gallus)
phospho-CRMP [cytosol]
(Drosophila melanogaster)
phospho-CRMP1 [cytosol]
(Bos taurus)
phospho-CRMP1 [cytosol]
(Canis familiaris)
phospho-CRMP1 [cytosol]
(Sus scrofa)
phospho-p-Y-CRMP1 [cytosol]
(Caenorhabditis elegans)
phospho-Crmp1 [cytosol]
(Mus musculus)
phospho-Crmp1 [cytosol]
(Rattus norvegicus)
phospho-crmp1 [cytosol]
(Xenopus tropicalis)
Modified Residues
Name
O4'-phospho-L-tyrosine at unknown position
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_001304.1
,
NP_001275590.1
,
NP_001275591.1
,
NP_001014809.1
OpenTargets
ENSG00000072832
GeneCards
Q14194
HPA
ENSG00000072832-CRMP1
Ensembl
ENSP00000380987
,
ENSG00000072832
,
ENSP00000321606
,
ENST00000397890
,
ENST00000324989
PRO
Q14194
Pharos - Targets
Q14194
PDB
4B3Z
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.703
14
UniProt:P08670 VIM
11
VIM(2-85) [cytosol]
(R-HSA-350264)
VIM(86-466) [cytosol]
(R-HSA-350294)
VIM(430-466) [cytosol]
(R-HSA-350316)
VIM(2-429) [cytosol]
(R-HSA-350317)
VIM(260-466) [cytosol]
(R-HSA-350314)
VIM(2-259) [cytosol]
(R-HSA-350323)
VIM [cytosol]
(R-HSA-201600)
Vimentin [late endosome lumen]
(R-HSA-9660019)
Vimentin [microtubule organizing center]
(R-HSA-9657898)
Vimentin [cytosol]
(R-HSA-9646687)
Vimentin [lysosomal lumen]
(R-HSA-9659977)
0.635
3
UniProt:P63244 RACK1
1
GNB2L1 [cytosol]
(R-HSA-5626956)
0.556
3
UniProt:P07900 HSP90AA1
8
HSP90AA1 [secretory granule lumen]
(R-HSA-6801515)
HSP90AA1 [ficolin-1-rich granule lumen]
(R-HSA-6801470)
HSP90AA1 [plasma membrane]
(R-HSA-534996)
HSP90AA1 [endocytic vesicle lumen]
(R-HSA-3221912)
HSP90AA1 [extracellular region]
(R-HSA-3221946)
HSP90AA1 [nucleoplasm]
(R-HSA-5082401)
HSP90AA1 [cytosol]
(R-HSA-192864)
HSP90AA1 [lysosomal lumen]
(R-HSA-9622850)
0.556
3
UniProt:P04183 TK1
1
TK1 [cytosol]
(R-HSA-73500)
0.553
2
UniProt:O15169 AXIN1
11
AXIN1 L396M [cytosol]
(R-HSA-5251503)
AXIN1 Y346* [cytosol]
(R-HSA-4839753)
AXIN1 E406* [cytosol]
(R-HSA-5251500)
AXIN1 W247* [cytosol]
(R-HSA-5251512)
AXIN1 P354L [cytosol]
(R-HSA-5251511)
AXIN1 P255S [cytosol]
(R-HSA-5251505)
ub-AXIN1 [cytosol]
(R-HSA-4641133)
Ub-RibC-AXIN1 [cytosol]
(R-HSA-3640864)
RibC-AXIN1 [cytosol]
(R-HSA-3640841)
p-T481,S486,S493-AXIN1 [cytosol]
(R-HSA-206040)
AXIN1 [cytosol]
(R-HSA-195249)
0.508
2
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