Reactome | p-Y-DPYSL3 [cytosol]

p-Y-DPYSL3 [cytosol]

Stable Identifier

R-HSA-399795

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Tyrosine phosphorylated CRMP-4

Locations in the PathwayBrowser

Expand all

Developmental Biology (Homo sapiens)

- Nervous system development (Homo sapiens)
  - Axon guidance (Homo sapiens)
    - Semaphorin interactions (Homo sapiens)
      - CRMPs in Sema3A signaling (Homo sapiens)
        
        Tyrosine phosphorylation of CRMPs by Fes (Homo sapiens)
        
        Sema3A:NP-1:Plexin-A:Fes:CRMP [plasma membrane] (Homo sapiens)
        
        pCRMP's tertramers (Y499) [cytosol] (Homo sapiens)
        
        Fes phosphorylated CRMP's 1-5 [cytosol] (Homo sapiens)
        
        p-Y-DPYSL3 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q14195 DPYSL3

Gene Names

DPYSL3, CRMP4, DRP3, ULIP, ULIP1

Chain

chain:1-570

Reference Genes

BioGPS Gene:1809 DPYSL3

COSMIC (genes):DPYSL3 DPYSL3

CTD Gene:1809 DPYSL3

dbSNP Gene:1809 DPYSL3

ENSEMBL:ENSG00000113657 DPYSL3

ENSEMBL_homo_sapiens_GENE:ENSG00000113657.13 DPYSL3

HGNC:3015 DPYSL3

KEGG Gene (Homo sapiens):1809 DPYSL3

Monarch:1809 DPYSL3

NCBI Gene:1809 DPYSL3

OMIM:601168 DPYSL3

UCSC:Q14195 DPYSL3

Reference Transcript

Other Identifiers

11715751_a_at

11751610_a_at

17001299

1809

201430_PM_s_at

201430_s_at

201431_PM_s_at

201431_s_at

2880291

2880293

2880294

2880295

2880301

2880303

2880305

2880306

2880308

2880309

2880313

2880314

2880317

2880319

2880320

2880321

2880322

2880331

2880332

2880333

2880334

2880346

2880347

2880348

2880349

2880350

36149_at

73128_at

8114920

A_23_P7528

A_24_P149036

D78014_at

GE57293

GO:0003824

GO:0005515

GO:0005576

GO:0005615

GO:0005737

GO:0005829

GO:0005856

GO:0007010

GO:0008092

GO:0010976

GO:0010977

GO:0016787

GO:0016810

GO:0016812

GO:0017124

GO:0030027

GO:0030154

GO:0030336

GO:0030426

GO:0031005

GO:0031410

GO:0031941

GO:0035374

GO:0042802

GO:0042995

GO:0043226

GO:0044297

GO:0045202

GO:0048666

GO:0048678

GO:0048856

GO:0048870

GO:0051017

GO:0051491

GO:0051764

GO:0070382

GO:0071345

HMNXSV003054309

Hs.74566.0.S1_3p_a_at

ILMN_1679262

PH_hs_0022676

TC05001909.hg

g4503378_3p_a_at

Participates

as a member of

Fes phosphorylated CRMP's 1-5 [cytosol] (Homo sapiens)

Other forms of this molecule

DPYSL3 [cytosol]

p-T509,T514,S518,S522-DPYSL3 [cytosol]

p-S522-DPYSL3 [cytosol]

Inferred To

phospho-DPYSL3 [cytosol] (Bos taurus)

phospho-DPYSL3 [cytosol] (Canis familiaris)

phospho-DPYSL3 [cytosol] (Gallus gallus)

phospho-DPYSL3 [cytosol] (Sus scrofa)

phospho-unc-33 [cytosol] (Caenorhabditis elegans)

phospho-dpysl3 [cytosol] (Danio rerio)

phospho-dpysl3 [cytosol] (Xenopus tropicalis)

phospho-CRMP [cytosol] (Drosophila melanogaster)

phospho-Dpysl3 [cytosol] (Mus musculus)

phospho-Dpysl3 [cytosol] (Rattus norvegicus)

Homologues of p-Y-DPYSL3 [cytosol] (Caenorhabditis elegans)

phospho-p-Y-DPYSL3 [cytosol] (Caenorhabditis elegans)

Modified Residues

Name

O4'-phospho-L-tyrosine at unknown position

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_001378.1, NP_001184223.1

OpenTargets

ENSG00000113657

HPA

ENSG00000113657-DPYSL3

GeneCards

Q14195

Ensembl

ENST00000343218, ENSG00000113657, ENSP00000381526, ENSP00000343690, ENST00000398514

PRO

Q14195

Pharos - Targets

Q14195

Orphanet

24438

HMDB Protein

HMDBP02980

PDB

4CNU, 4CNS, 4CNT, 4BKN