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MARCKS [plasma membrane]
Stable Identifier
R-HSA-399985
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
MARCS_HUMAN, Myristoylated alanine-rich C-kinase substrate
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Integration of energy metabolism (Homo sapiens)
Regulation of insulin secretion (Homo sapiens)
Acetylcholine regulates insulin secretion (Homo sapiens)
Protein kinase C, alpha type phosphorylates MARCKS (Homo sapiens)
MARCKS [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P29966 MARCKS
Gene Names
MARCKS, MACS, PRKCSL
Chain
initiator methionine:, chain:2-332
Reference Genes
BioGPS Gene:4082 MARCKS
COSMIC (genes):MARCKS MARCKS
CTD Gene:4082 MARCKS
dbSNP Gene:4082 MARCKS
ENSEMBL:ENSG00000277443 MARCKS
ENSEMBL_homo_sapiens_GENE:ENSG00000277443.3 MARCKS
HGNC:6759 MARCKS
KEGG Gene (Homo sapiens):4082 MARCKS
Monarch:4082 MARCKS
NCBI Gene:4082 MARCKS
OMIM:177061 MARCKS
UCSC:P29966 MARCKS
Reference Transcript
RefSeq:NM_002356.6 MARCKS
Other Identifiers
11742948_at
11757816_s_at
17011832
201668_PM_x_at
201668_x_at
201669_PM_s_at
201669_s_at
201670_PM_s_at
201670_s_at
225897_PM_at
225897_at
2922216
2922217
2922218
2922219
2922222
2922223
2922224
2922225
2922226
2922227
2922228
2922229
2922230
2922231
2922232
2922233
2922234
2922235
2922236
32434_at
3927352
3927354
4082
48081_at
8121563
A_23_P214222
D10522_at
GE61460
GO:0003779
GO:0005080
GO:0005516
GO:0005576
GO:0005615
GO:0005634
GO:0005737
GO:0005813
GO:0005815
GO:0005856
GO:0005886
GO:0005925
GO:0005938
GO:0006915
GO:0007005
GO:0007010
GO:0007015
GO:0007417
GO:0008092
GO:0012501
GO:0015629
GO:0016020
GO:0021915
GO:0022008
GO:0030154
GO:0032432
GO:0034976
GO:0042585
GO:0042802
GO:0043226
GO:0048856
GO:0051015
GO:0051017
GO:0051764
GO:0070062
HMNXSV003011814
Hs.330716.0.S1_3p_at
Hs.75607.0.S1_3p_a_at
ILMN_1807042
PH_hs_0029733
TC06000909.hg
TC06003006.hg
g11125771_3p_s_at
g187386_3p_a_at
Participates
as an input of
Protein kinase C, alpha type phosphorylates MARCKS (Homo sapiens)
Other forms of this molecule
p-4S-MARCKS [plasma membrane]
Inferred To
MARCKS [plasma membrane]
(Bos taurus)
MARCKS [plasma membrane]
(Canis familiaris)
MARCKS [plasma membrane]
(Gallus gallus)
MARCKS [plasma membrane]
(Sus scrofa)
Marcks [plasma membrane]
(Mus musculus)
Marcks [plasma membrane]
(Rattus norvegicus)
marcks [plasma membrane]
(Xenopus tropicalis)
marcksa [plasma membrane]
(Danio rerio)
Cross References
RefSeq
NP_002347.5
OpenTargets
ENSG00000277443
HPA
ENSG00000277443-MARCKS
GeneCards
P29966
Ensembl
ENSG00000277443
,
ENSP00000478061
,
ENST00000612661
PRO
P29966
Pharos - Targets
P29966
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.615
14
UniProt:P10636-8 MAPT
3
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
MAPT-8 [cytosol]
(R-HSA-9619519)
0.527
5
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