Reactome | p-S-CRY2 [cytosol]

p-S-CRY2 [cytosol]

Stable Identifier

R-HSA-400305

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

p-CRY2, Phosphorylated Cryptochrome-2, CRY2_HUMAN

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External Reference Information

External Reference

UniProt:Q49AN0 CRY2

Gene Names

CRY2, KIAA0658

Chain

chain:1-593

Reference Genes

BioGPS Gene:1408 CRY2

COSMIC (genes):CRY2 CRY2

CTD Gene:1408 CRY2

dbSNP Gene:1408 CRY2

ENSEMBL:ENSG00000121671 CRY2

HGNC:2385 CRY2

Monarch:1408 CRY2

NCBI Gene:1408 CRY2

OMIM:603732 CRY2

UCSC:Q49AN0 CRY2

Reference Transcript

Other Identifiers

11719310_a_at

11719311_a_at

1408

16724194

212695_PM_at

212695_at

3329037

3329038

3329039

3329041

3329042

3329043

3329044

3329045

3329046

3329048

3329049

3329052

3329053

3329054

3329055

3329058

3329059

3329060

3329061

3329062

3329063

3329064

3329065

3329066

3329067

3329068

35852_at

7939595

A_14_P133733

A_23_P127394

A_23_P388027

A_24_P158587

GE53368

GO:0000122

GO:0000166

GO:0000976

GO:0003677

GO:0003684

GO:0003697

GO:0003824

GO:0005515

GO:0005576

GO:0005634

GO:0005737

GO:0005739

GO:0005829

GO:0006355

GO:0006606

GO:0006886

GO:0006913

GO:0007623

GO:0009416

GO:0009785

GO:0009881

GO:0009882

GO:0014823

GO:0016607

GO:0016829

GO:0016922

GO:0019900

GO:0019901

GO:0019902

GO:0019915

GO:0032515

GO:0032868

GO:0032922

GO:0042593

GO:0042752

GO:0042754

GO:0043153

GO:0043226

GO:0045892

GO:0048511

GO:0060089

GO:0071949

GO:1990512

GO:2000118

GO:2000323

GO:2000850

HMNXSV003017990

Hs.7278.0.S1_3p_at

ILMN_1796180

PH_hs_0000749

TC11000388.hg

Participates

as a member of

p-CRY1,p-CRY2 [cytosol] (Homo sapiens)

Other forms of this molecule

p-S-CRY2 [nucleoplasm]

CRY2 [cytosol]

Ub-p-S-CRY2 [nucleoplasm]

Modified Residues

Name

O-phospho-L-serine at unknown position

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

OpenTargets

ENSG00000121671

ENSEMBL

ENSP00000397419, ENST00000616080, ENST00000417225, ENSP00000484684

HPA

ENSG00000121671-CRY2

PRO

Q49AN0

Pharos - Targets

Q49AN0

HMDB Protein

HMDBP08265

Interactors (39)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P49674 CSNK1E	2	CSNK1E [cytosol] (R-HSA-205877) CSNK1E [nucleoplasm] (R-HSA-421306)	0.643	5
UniProt:Q12933 TRAF2	5	TRAF2 [cytosol] (R-HSA-66370) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) TRAF2 [nucleoplasm] (R-HSA-8862199)	0.556	3
UniProt:Q9H0D6 XRN2	2	XRN2 [nucleoplasm] (R-HSA-6791205) XRN2 [cytosol] (R-HSA-391297)	0.556	3
UniProt:P0DPK4 NOTCH2NLC	1	NOTCH2NLC [extracellular region] (R-HSA-9908932)	0.556	3
UniProt:A8MQ03 CRTP1			0.556	3
UniProt:B2RXF5 ZBT42			0.556	3
UniProt:Q9BYQ0 KRTAP9-8	1	KRTAP9-8 [cytosol] (R-HSA-6809953)	0.556	3
UniProt:Q6A162 KRT40	1	KRT40 [cytosol] (R-HSA-6809605)	0.556	3
UniProt:P28799 GRN	2	GRN [azurophil granule lumen] (R-HSA-6799168) GRN [extracellular region] (R-HSA-6806217)	0.556	3
UniProt:Q6L8H1 KRTAP5-4	1	KRTAP5-4 [cytosol] (R-HSA-6810264)	0.556	3
UniProt:P0C264 SBK3			0.556	3
UniProt:Q5JR59 MTUS2			0.556	3
UniProt:Q2TAL6 VWC2			0.556	3
UniProt:Q8WZ60 KLHL6			0.556	5
UniProt:Q6L8G8 KRTAP5-7	1	KRTAP5-7 [cytosol] (R-HSA-6810273)	0.556	3
UniProt:Q13363-2 CTBP1			0.556	3
UniProt:Q07627 KRTAP1-1	1	KRTAP1-1 [cytosol] (R-HSA-6809855)	0.556	3
UniProt:P60410 KRTAP10-8	1	KRTAP10-8 [cytosol] (R-HSA-6810301)	0.556	3
UniProt:Q5JR59-3 MTUS2			0.556	5
UniProt:O76083-2 PDE9A			0.556	3
UniProt:Q9H190 SDCB2			0.556	3
UniProt:Q701N4 KRTAP5-2	1	KRTAP5-2 [cytosol] (R-HSA-6810291)	0.556	3
UniProt:P60409 KRTAP10-7	1	KRTAP10-7 [cytosol] (R-HSA-6810279)	0.556	3
UniProt:Q13077 TRAF1	3	TRAF1 [cytosol] (R-HSA-5634163) TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.556	3
UniProt:Q3LI70 KRTAP19-6	1	KRTAP19-6 [cytosol] (R-HSA-6810286)	0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [plasma membrane] (R-HSA-416989) PICK1 [endocytic vesicle membrane] (R-HSA-417017)	0.556	3
UniProt:Q9BYR5 KRTAP4-2	1	KRTAP4-2 [cytosol] (R-HSA-6809948)	0.556	3
UniProt:O15344 MID1	1	MID1 [cytosol] (R-HSA-976027)	0.556	3
UniProt:O95544 NADK	1	NADK [cytosol] (R-HSA-197282)	0.556	3
UniProt:Q6L8H4 KRTAP5-1	1	KRTAP5-1 [cytosol] (R-HSA-6810297)	0.556	3
UniProt:P26371 KRTAP5-9	1	KRTAP5-9 [cytosol] (R-HSA-6810265)	0.556	3
UniProt:Q8IUG1 KRTAP1-3	1	KRTAP1-3 [cytosol] (R-HSA-6809866)	0.556	3
UniProt:O76083 PDE9A	1	PDE9A [cytosol] (R-HSA-418533)	0.556	3
UniProt:Q3LI67 KRTAP6-3	1	KRTAP6-3 [cytosol] (R-HSA-6810281)	0.556	3
UniProt:Q9UKT7 FBXL3	2	FBXL3 [nucleoplasm] (R-HSA-400380) FBXL3 [cytosol] (R-HSA-391289)	0.527	4
UniProt:Q16526 CRY1	4	Ub-p-S-CRY1 [nucleoplasm] (R-HSA-517931) CRY1 [cytosol] (R-HSA-400247) p-S-CRY1 [nucleoplasm] (R-HSA-400340) p-S-CRY1 [cytosol] (R-HSA-400270)	0.527	3
UniProt:P63208 SKP1	2	SKP1 [cytosol] (R-HSA-174150) SKP1 [nucleoplasm] (R-HSA-187538)	0.527	4
UniProt:P48730 CSNK1D	3	CSNK1D [nucleoplasm] (R-HSA-421305) CSNK1D [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5685717) CSNK1D [cytosol] (R-HSA-380315)	0.527	3
UniProt:P53041 PPP5C	2	PPP5C [nucleoplasm] (R-HSA-5683410) PPP5C [cytosol] (R-HSA-5675402)	0.499	3

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