Reactome | PER1 [cytosol]

PER1 [cytosol]

Stable Identifier

R-HSA-400373

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Period circadian protein homolog 1, PER1_HUMAN

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O15534 PER1

Gene Names

PER1, KIAA0482, PER, RIGUI

Chain

chain:1-1290

Reference Genes

BioGPS Gene:5187 PER1

COSMIC (genes):PER1 PER1

CTD Gene:5187 PER1

dbSNP Gene:5187 PER1

ENSEMBL:ENSG00000179094 PER1

ENSEMBL:ENSG00000179094.16 PER1

HGNC:8845 PER1

KEGG Gene (Homo sapiens):5187 PER1

Monarch:5187 PER1

NCBI Gene:5187 PER1

OMIM:602260 PER1

UCSC:O15534 PER1

Reference Transcript

Other Identifiers

11717168_a_at

11747289_a_at

11760378_at

16840846

202861_PM_at

202861_at

242832_PM_at

242832_at

36829_PM_at

36829_at

3744151

3744152

3744153

3744156

3744158

3744159

3744160

3744163

3744164

3744165

3744166

3744167

3744168

3744169

3744170

3744171

3744172

3744175

3744176

3744177

3744178

3744179

3744181

3744182

3744183

3744185

3744187

3744189

3744192

3744195

3744197

3744198

3744199

3744200

3744201

3744202

3744203

3744208

3744213

43608_at

5187

8012349

A_23_P89589

A_24_P93916

GE81168

GO:0000122

GO:0000976

GO:0000978

GO:0001222

GO:0002028

GO:0003677

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006325

GO:0006338

GO:0006351

GO:0006355

GO:0006954

GO:0007623

GO:0009649

GO:0010608

GO:0019900

GO:0023052

GO:0031490

GO:0031625

GO:0032922

GO:0042634

GO:0042752

GO:0043124

GO:0043153

GO:0043226

GO:0045892

GO:0045944

GO:0046329

GO:0048511

GO:0051591

GO:0070888

GO:0097167

GO:0140297

GO:1900015

GO:1900744

GO:2000323

HMNXSV003009693

Hs.193762.0.A1_3p_at

ILMN_1653125

PH_hs_0026050

TC17002849.hg

g4505712_3p_s_at

Participates

as an output of

Expression of PERIOD-1 (Homo sapiens)

as a member of

PER1,PER2 [cytosol] (Homo sapiens)

Other forms of this molecule

p-S-PER1 [cytosol]

p-S-PER1 [nucleoplasm]

Ub-p-S-PER1 [cytosol]

Cross References

RefSeq

XP_005256746.1, NP_002607.2

OpenTargets

ENSG00000179094

HPA

ENSG00000179094-PER1

GeneCards

O15534

Ensembl

ENSP00000314420, ENSP00000346979, ENST00000317276, ENST00000354903, ENSG00000179094

PRO

O15534

Pharos - Targets

O15534

Interactors (34)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P49674 CSNK1E	2	CSNK1E [nucleoplasm] (R-HSA-421306) CSNK1E [cytosol] (R-HSA-205877)	0.788	5
UniProt:P97784 Cry1	4	Cry1 [cytosol] (R-MMU-508637) p-Cry1 [cytosol] (R-MMU-508644) p-Cry1 [nucleoplasm] (R-MMU-508662) ub-p-Cry1 [nucleoplasm] (R-MMU-517961)	0.564	3
UniProt:O75460-2 ERN1			0.556	3
UniProt:P22607 FGFR3	20	FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane] (R-HSA-8853144) FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane] (R-HSA-8853131) FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane] (R-HSA-8853152) FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane] (R-HSA-8853124) FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane] (R-HSA-8853125) FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] (R-HSA-8853127) FGFR3 K650T [plasma membrane] (R-HSA-1614411) FGFR3 K650N [plasma membrane] (R-HSA-1614406) FGFR3 K650M [plasma membrane] (R-HSA-1614402) FGFR3 K650Q [plasma membrane] (R-HSA-1614410) FGFR3 A391E [plasma membrane] (R-HSA-1614390) FGFR3 K650E [plasma membrane] (R-HSA-1614400) FGFR3 G380R [plasma membrane] (R-HSA-1614398) FGFR3 G382D [plasma membrane] (R-HSA-2018740) FGFR3 805fs*141 [plasma membrane] (R-HSA-1614387) FGFR3 [plasma membrane] (R-HSA-2038357) FGFR3 S371C [plasma membrane] (R-HSA-1614421) FGFR3 Y373C [plasma membrane] (R-HSA-1614424) FGFR3 G370C [plasma membrane] (R-HSA-1614394) FGFR3 R248C [plasma membrane] (R-HSA-1614419)	0.556	3
UniProt:Q99832 CCT7	1	CCT7 [cytosol] (R-HSA-390451)	0.556	3
UniProt:P49591 SARS1	1	SARS [cytosol] (R-HSA-379691)	0.556	3
UniProt:P60201-2 PLP1			0.556	3
UniProt:O75400-2 PRPF40A			0.556	3
UniProt:P41091 EIF2S3	1	EIF2S3 [cytosol] (R-HSA-72514)	0.556	3
UniProt:P62826 RAN	2	RAN [nucleoplasm] (R-HSA-165528) RAN [cytosol] (R-HSA-165540)	0.556	3
UniProt:O60333-2 KIF1B			0.556	3
UniProt:O60356 NUPR1			0.556	3
UniProt:P54652 HSPA2	2	HSPA2 [cytosol] (R-HSA-3371408) HSPA2 [nucleoplasm] (R-HSA-912480)	0.556	3
UniProt:P29692-2 EEF1D			0.556	3
UniProt:Q8WXH2 JPH3			0.556	3
UniProt:Q0VDC6 Q0VDC6			0.556	3
UniProt:Q9UMX0 UBQLN1	1	UBQLN1 [cytosol] (R-HSA-8866006)	0.556	3
UniProt:P14136 GFAP	3	p-GFAP [lysosomal membrane] (R-HSA-9626054) GFAP [lysosomal membrane] (R-HSA-9625195) GFAP [cytosol] (R-HSA-1253311)	0.556	3
UniProt:P60891 PRPS1	1	PRPS1 [cytosol] (R-HSA-73483)	0.556	3
UniProt:P06396 GSN	7	GSN(200-270) [extracellular region] (R-HSA-976940) GSN [secretory granule lumen] (R-HSA-6801486) GSN [extracellular region] (R-HSA-6806510) GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN(404-782) [cytosol] (R-HSA-350272) GSN(28-403) [cytosol] (R-HSA-201618) GSN [cytosol] (R-HSA-350275)	0.556	3
UniProt:P04792 HSPB1	3	HSPB1 [cytosol] (R-HSA-450563) p-S15,S78,S82-HSP27 [cytosol] (R-HSA-5218697) p-S78,S82 HSPB1 [cytosol] (R-HSA-5687009)	0.556	3
UniProt:Q8WUW1 BRK1	1	BRK1 [cytosol] (R-HSA-1671645)	0.556	3
UniProt:P07237 P4HB	3	P4HB [endoplasmic reticulum lumen] (R-HSA-174692) p-P4HB [endoplasmic reticulum lumen] (R-HSA-8956902) HC53,56-P4HB [endoplasmic reticulum lumen] (R-HSA-3341287)	0.556	3
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:Q92870-2 Q928702			0.556	3
IntAct:EBI-25847655 CCSB			0.556	3
UniProt:O14901 KLF11			0.556	3
UniProt:P55212 CASP6	5	CASP6(194-293) [nucleoplasm] (R-HSA-352246) CASP6(24-179) [nucleoplasm] (R-HSA-352247) CASP6(24-179) [cytosol] (R-HSA-350313) CASP6(194-293) [cytosol] (R-HSA-266128) CASP6 (1-293) [cytosol] (R-HSA-6798132)	0.556	3
UniProt:P46379-2 BAG6			0.556	3
UniProt:P01112 HRAS	20	HRAS Q61R [plasma membrane] (R-HSA-6802458) HRAS Q61L [plasma membrane] (R-HSA-6802452) HRAS Q61K [plasma membrane] (R-HSA-6802442) HRAS G13R [plasma membrane] (R-HSA-6802368) HRAS G12V [plasma membrane] (R-HSA-6802350) HRAS G12S [plasma membrane] (R-HSA-6802343) HRAS T58I [plasma membrane] (R-HSA-9656014) HRAS G13C [plasma membrane] (R-HSA-9656008) HRAS K117R [plasma membrane] (R-HSA-9656010) HRAS G13V [plasma membrane] (R-HSA-9656579) HRAS G13D [plasma membrane] (R-HSA-9656572) HRAS G13S [plasma membrane] (R-HSA-9656574) HRAS K117N [plasma membrane] (R-HSA-9656603) HRAS G12D [plasma membrane] (R-HSA-9656564) HRAS G12C [plasma membrane] (R-HSA-9656561) S-Farn-Me HRAS [plasma membrane] (R-HSA-9665052) HRAS [plasma membrane] (R-HSA-62717) S-Farn-Me PalmS HRAS [Golgi membrane] (R-HSA-9647896) S-Farn-Me HRAS [endoplasmic reticulum membrane] (R-HSA-9647796) S-Farn-HRAS [endoplasmic reticulum membrane] (R-HSA-9647788)	0.556	3
UniProt:P28799 GRN	2	GRN [azurophil granule lumen] (R-HSA-6799168) GRN [extracellular region] (R-HSA-6806217)	0.556	3
UniProt:Q14957 GRIN2C	3	GRIN2C [endoplasmic reticulum membrane] (R-HSA-9609761) GRIN2C [plasma membrane] (R-HSA-419560) p-Y-GRIN2C [plasma membrane] (R-HSA-9612189)	0.556	3
UniProt:Q9P1I4 Q9P1I4			0.556	3
UniProt:Q9R194 Cry2	4	ub-p-Cry2 [nucleoplasm] (R-MMU-517964) p-Cry2 [nucleoplasm] (R-MMU-508638) p-Cry2 [cytosol] (R-MMU-508666) Cry2 [cytosol] (R-MMU-508614)	0.499	3

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