SUMOylation of SUMOylation proteins

Stable Identifier
R-HSA-4085377
Type
Pathway
Species
Homo sapiens
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SUMOylation processes themselves can be controlled by SUMOylation (reviewed in Wilkinson and Henley 2010). The SUMO E3 ligases PIAS4, RANBP2, and TOPORS are SUMOylated, as is the single SUMO E2 enzyme, UBE2I (UBC9). SUMOylation affects the subcellular location of PIAS4 and TOPORS and affects the activity of PIAS4 and UBE2I.

Literature References
PubMed ID Title Journal Year
20462400 Mechanisms, regulation and consequences of protein SUMOylation

Wilkinson, KA, Henley, JM

Biochem. J. 2010
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