Reactome: A Curated Pathway Database

PP2A-PPP2R2A dephosphorylates FOXM1

Stable Identifier
R-HSA-4088141
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

FOXM1 can bind the regulatory subunit B55-alpha (PPP2R2A) of serine/threonine-protein phosphatase 2A (PP2A). PP2A dephosphorylates FOXM1, preventing its premature activation (Alvarez-Fernandez et al. 2011).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
protein serine/threonine phosphatase activity of PP2A-PPP2R2A [nucleoplasm] PP2A-PPP2R2A [nucleoplasm] protein serine/threonine phosphatase activity (0004722)
Orthologous Events