Reactome | SUMO1-K32-HIPK2 [nucleoplasm]

SUMO1-K32-HIPK2 [nucleoplasm]

Stable Identifier

R-HSA-4090405

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Homeodomain-interacting protein kinase 2

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Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - SUMOylation (Homo sapiens)
    - SUMO E3 ligases SUMOylate target proteins (Homo sapiens)
      - SUMOylation of transcription cofactors (Homo sapiens)
        
        SUMOylation of HIPK2 with SUMO1 (Homo sapiens)
        
        SUMO1:HIPK2 [nucleoplasm] (Homo sapiens)
        
        SUMO1-K32-HIPK2 [nucleoplasm] (Homo sapiens)

General

Hoffmann et al. 2005 (205) and Gresko et al. (2005) cite lysine-25 as the SUMO-modified residue, however the motif in their papers indicates lysine-32 of the UniProt sequence is the lysine residue modified.

Literature References

PubMed ID	Title	Journal	Year
15958389	Regulation of homeodomain-interacting protein kinase 2 (HIPK2) effector function through dynamic small ubiquitin-related modifier-1 (SUMO-1) modification Hofmann, TG, Jaffray, E, Stollberg, N, Hay, RT, Will, H	J. Biol. Chem.	2005
15766567	Covalent modification of human homeodomain interacting protein kinase 2 by SUMO-1 at lysine 25 affects its stability Gresko, E, Möller, A, Roscic, A, Schmitz, ML	Biochem. Biophys. Res. Commun.	2005

External Reference Information

External Reference

UniProt:Q9H2X6 HIPK2

Gene Names

HIPK2

Chain

chain:1-1198

Reference Genes

BioGPS Gene:28996 HIPK2

COSMIC (genes):HIPK2 HIPK2

CTD Gene:28996 HIPK2

dbSNP Gene:28996 HIPK2

ENSEMBL:ENSG00000064393 HIPK2

ENSEMBL_homo_sapiens_GENE:ENSG00000064393 HIPK2

HGNC:14402 HIPK2

KEGG Gene (Homo sapiens):28996 HIPK2

Monarch:28996 HIPK2

NCBI Gene:28996 HIPK2

OMIM:606868 HIPK2

UCSC:Q9H2X6 HIPK2

Reference Transcript

Other Identifiers

0006520139

11719404_a_at

11719405_a_at

11719406_a_at

11719407_a_at

11719408_a_at

11719409_a_at

11719410_s_at

11752111_a_at

17063461

213763_at

219028_at

224066_s_at

225097_at

225115_at

225116_at

225368_at

28996

3075779

3075780

3075781

3075782

3075783

3075784

3075785

3075786

3075787

3075788

3075789

3075796

3075798

3075799

3075800

3075802

3075804

3075805

3075810

3075812

3075814

3075816

3075817

3075818

3075849

3075868

3075869

37851_at

44036_at

55913_at

56287_at

72576_at

7611

80844_at

8143307

85541_at

A_19_P00315668

A_19_P00321851

A_23_P169756

A_23_P169766

A_24_P500621

A_24_P681011

A_33_P3223121

AAG35710

AAG41236

AAL37371

AAS00368

AC005531

AC006021

AC073184

AC141932

AF207702

AF208291

AF326592

CCDS75666

CCDS75667

ENSG00000064393

ENSP00000385571

ENSP00000413724

ENST00000406875

ENST00000406875.7

ENST00000428878

ENST00000428878.6

EntrezGene:28996

g13430859_3p_at

g13430859_3p_x_at

GE537256

GE54515

GE58192

GO:0000122

GO:0000166

GO:0001102

GO:0001654

GO:0001934

GO:0002376

GO:0003674

GO:0003713

GO:0003714

GO:0004672

GO:0004674

GO:0005515

GO:0005524

GO:0005575

GO:0005634

GO:0005654

GO:0005737

GO:0006464

GO:0006468

GO:0006915

GO:0006950

GO:0006974

GO:0006978

GO:0007165

GO:0007179

GO:0007224

GO:0007628

GO:0008134

GO:0008219

GO:0008284

GO:0008344

GO:0009952

GO:0010842

GO:0016301

GO:0016310

GO:0016604

GO:0016605

GO:0016740

GO:0018105

GO:0018107

GO:0019048

GO:0030154

GO:0030182

GO:0030218

GO:0030511

GO:0030514

GO:0030578

GO:0032092

GO:0032991

GO:0042592

GO:0042771

GO:0043167

GO:0043226

GO:0043388

GO:0043524

GO:0044403

GO:0045766

GO:0045893

GO:0045944

GO:0046330

GO:0046332

GO:0046790

GO:0048596

GO:0048646

GO:0048856

GO:0050882

GO:0051091

GO:0051726

GO:0060059

GO:0060235

GO:0060395

GO:0061072

GO:0071456

GO:0090575

GO:0097193

GO:1901796

GO:2000059

H7BXX9

HGNC:14402

HIPK2

HIPK2-202

HIPK2-203

HPA007611

Hs.13417.0.S1_3p_at

Hs.21906.0.A1_3p_at

Hs.75354.1.S1_3p_at

Hs.75354.1.S2_3p_at

Hs.75354.1.S3_3p_at

ILMN_1687440

ILMN_1719828

ILMN_1881948

ILMN_1912737

IPR000719

IPR008271

IPR011009

IPR017441

MIM:606868

NM_001113239

NM_022740

NP_001106710

NP_073577

PF00069

PH_hs_0024580

PH_hs_0039041

SM00220

TC07001915.hg

TC07003195.hg

UPI000002AB1E

UPI000012C71E

XM_006715935

XM_011516077

XM_011516078

XM_011516079

XM_011516080

XM_011516081

XM_017012069

XP_006715998

XP_011514379

XP_011514380

XP_011514381

XP_011514382

XP_011514383

XP_016867558

Participant Of

hasComponent

SUMO1:HIPK2 [nucleoplasm]

Other forms of this molecule

p-HIPK2 [nucleoplasm]

HIPK2 [nucleoplasm]

Inferred To

SUMO1-K32-HIPK2 [nucleoplasm] (Bos taurus)

SUMO1-K32-HIPK2 [nucleoplasm] (Caenorhabditis elegans)

SUMO1-K32-HIPK2 [nucleoplasm] (Canis familiaris)

SUMO1-K32-HIPK2 [nucleoplasm] (Dictyostelium discoideum)

SUMO1-K32-HIPK2 [nucleoplasm] (Gallus gallus)

SUMO1-K32-HIPK2 [nucleoplasm] (Mus musculus)

SUMO1-K32-HIPK2 [nucleoplasm] (Rattus norvegicus)

SUMO1-K32-HIPK2 [nucleoplasm] (Saccharomyces cerevisiae)

SUMO1-K32-HIPK2 [nucleoplasm] (Schizosaccharomyces pombe)

SUMO1-K32-HIPK2 [nucleoplasm] (Sus scrofa)

SUMO1-K32-HIPK2 [nucleoplasm] (Xenopus tropicalis)

Modified Residues

Name

Inter-chain Crosslink via sumoylated lysine at 32 and 97

Coordinate

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Cross References

RefSeq

NP_001106710.1, NP_073577.3

ZINC - World Drugs

HIPK2_HUMAN

OpenTargets

ENSG00000064393

ZINC - FDA approved

HIPK2_HUMAN

ZINC - Substances

HIPK2_HUMAN

GeneCards

Q9H2X6

ZINC target

Q9H2X6

PRO

Q9H2X6

ZINC - Predictions - Purchasable

HIPK2_HUMAN

HMDB Protein

HMDBP09471

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P63279 UBE2I	8	SUMO1-C93-UBE2I [cytosol] (R-HSA-4656909) SUMO1-K14-UBE2I [nucleoplasm] (R-HSA-4085358) UBE2I [nuclear envelope] (R-HSA-4655408) UBE2I [cytosol] (R-HSA-4655342) SUMO3-C93-UBE2I [nucleoplasm] (R-HSA-3730629) SUMO2-C93-UBE2I [nucleoplasm] (R-HSA-3730619) UBE2I [nucleoplasm] (R-HSA-912481) SUMO1-C93-UBE2I [nucleoplasm] (R-HSA-3730617)	0.721	5
UniProt:P04637 TP53	27	TP53 [cytosol] (R-HSA-8869337) Unfolded TP53 [cytosol] (R-HSA-6813797) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) SUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) Ac-K120,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6805656) Ac-K120,K382,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6805631) Ac-K382,p-S15,S20-TP53 [nucleoplasm] (R-HSA-5628868) PolyUb,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6804446) p-S315-TP53 [nucleoplasm] (R-HSA-6805106) p-S15,S20,S269,T284-TP53 [nucleoplasm] (R-HSA-6805133) p-S15,S33,S46-TP53 [nucleoplasm] (R-HSA-6805268) p-S15,S392-TP53 [nucleoplasm] (R-HSA-3222015) p-T55-TP53 [nucleoplasm] (R-HSA-6805400) p-S15,S20,S46-TP53 [nucleoplasm] (R-HSA-6798369) p-S15,S20,S392-TP53 [nucleoplasm] (R-HSA-6805053) p-S37-TP53 [nucleoplasm] (R-HSA-3239022) Me2K-370,382-TP53 [nucleoplasm] (R-HSA-3222242) Me1-K372,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6805719) p-S15,S20,Me-R333,Me2-R335,R337-TP53 [nucleoplasm] (R-HSA-6804378) Me-K382,p-S15,S20-TP53 [nucleoplasm] (R-HSA-3222124) Me2-K373-TP53 [nucleoplasm] (R-HSA-6805759) MeK-370,p-S15,S20-TP53 [nucleoplasm] (R-HSA-3222226) PolyUb-TP53 [nucleoplasm] (R-HSA-6793679) PolyUb-TP53 [cytosol] (R-HSA-6793681) p-S15,S20-TP53 [nucleoplasm] (R-HSA-69683) p-S15-TP53 [nucleoplasm] (R-HSA-69507) TP53 [nucleoplasm] (R-HSA-69488)	0.713	3
UniProt:P61962 DCAF7	2	DCAF7 [nucleoplasm] (R-HSA-8863312) Unfolded DCAF7 [cytosol] (R-HSA-6813821)	0.645	10
UniProt:Q01196 RUNX1	5	RUNX1 [nucleoplasm] (R-HSA-8865295) RUNX1 [plasma membrane] (R-HSA-5667138) p-7Y-RUNX1 [nucleoplasm] (R-HSA-8937712) MeR206,MeR210-RUNX1 [nucleoplasm] (R-HSA-8934750) p-S249,S273,T276-RUNX1 [nucleoplasm] (R-HSA-8878063)	0.639	4
UniProt:Q00987 MDM2	11	SUMO1-K182-MDM2 [nucleoplasm] (R-HSA-3000408) PolyUb-MDM2 [nucleoplasm] (R-HSA-6782472) MDM2 [plasma membrane] (R-HSA-416843) MDM2 [endocytic vesicle membrane] (R-HSA-416849) p-S166,S188,T218-MDM2 [nucleoplasm] (R-HSA-6792862) PolyUb,p-S166,S188-MDM2 [nucleoplasm] (R-HSA-6795669) p-5S,T-MDM2 [nucleoplasm] (R-HSA-6804954) MDM2 [nucleoplasm] (R-HSA-69486) MDM2 [cytosol] (R-HSA-198644) p-S166,S188-MDM2 [cytosol] (R-HSA-198638) p-S166,S188-MDM2 [nucleoplasm] (R-HSA-6793669)	0.62	5
UniProt:Q09472 EP300	5	Foxo4-S-S-EP300 [nucleoplasm] (R-HSA-9617720) SUMO1-K1020,1024-EP300 [nucleoplasm] (R-HSA-3899306) FOXO4-S-S-EP300 [nucleoplasm] (R-HSA-9617691) p-S,T-EP300 [nucleoplasm] (R-HSA-8878072) EP300 [nucleoplasm] (R-HSA-381325)	0.602	4
UniProt:Q04724 TLE1	2	TLE1 [nucleoplasm] (R-HSA-212327) Ub-TLE1 [nucleoplasm] (R-HSA-3322369)	0.544	2
UniProt:P63165 SUMO1	155	TOPORS-G97-SUMO1 [nucleoplasm] (R-HSA-4551623) K14-UBE2I-G97-SUMO1 [nucleoplasm] (R-HSA-4085334) PIAS4-G97-SUMO1 [nucleoplasm] (R-HSA-3968375) K2592-RANBP2-G97-SUMO1 [nuclear envelope] (R-HSA-4551627) K2723-RANBP2-G97-SUMO1 [nuclear envelope] (R-HSA-4551737) K2650-RANBP2-G97-SUMO1 [nuclear envelope] (R-HSA-4551591) K196-VHL-G97-SUMO1 [nucleoplasm] (R-HSA-4551630) K171-VHL-G97-SUMO1 [nucleoplasm] (R-HSA-4551632) K159-VHL-G97-SUMO1 [nucleoplasm] (R-HSA-4551713) MDM-G97-SUMO1 [nucleoplasm] (R-HSA-3730829) K575-TRIM28-G97-SUMO1 [nucleoplasm] (R-HSA-4090305) K804-TRIM28-G97-SUMO1 [nucleoplasm] (R-HSA-3782561) K750-TRIM28-G97-SUMO1 [nucleoplasm] (R-HSA-4090298) K676-TRIM28-G97-SUMO1 [nucleoplasm] (R-HSA-4090396) K554-TRIM28-G97-SUMO1 [nucleoplasm] (R-HSA-3782555) K779-TRIM28-G97-SUMO1 [nucleoplasm] (R-HSA-3782585) ING2-G97-SUMO1 [nucleoplasm] (R-HSA-4086096) K788-Ncoa2-G97-SUMO1 [nucleoplasm] (R-HSA-4085297) K731-Ncoa2-G97-SUMO1 [nucleoplasm] (R-HSA-4085312) K239-Ncoa2-G97-SUMO1 [nucleoplasm] (R-HSA-4085320) K239-NCOA2-G97-SUMO1 [nucleoplasm] (R-HSA-4085299) K731-NCOA2-G97-SUMO1 [nucleoplasm] (R-HSA-4085290) K788-NCOA2-G97-SUMO1 [nucleoplasm] (R-HSA-4085308) NPM1-G97-SUMO1 [nucleoplasm] (R-HSA-4086019) NCOR2-G97-SUMO1 [nucleoplasm] (R-HSA-3927883) DDX17-G97-SUMO1 [nucleoplasm] (R-HSA-3900210) PARK7-G97-SUMO1 [nucleoplasm] (R-HSA-4085344) K1033-CREBBP-G97-SUMO1 [nucleoplasm] (R-HSA-3927910) K1056-CREBBP-G97-SUMO1 [nucleoplasm] (R-HSA-3927954) K998-CREBBP-G97-SUMO1 [nucleoplasm] (R-HSA-3927822) K1154-NRIP1-G97-SUMO1 [nucleoplasm] (R-HSA-4086067) K756-NRIP1-G97-SUMO1 [nucleoplasm] (R-HSA-4086034) DDX5-G97-SUMO1 [nucleoplasm] (R-HSA-3900212) CASP8AP2-G97-SUMO1 [nucleoplasm] (R-HSA-3927863) K1024-EP300-G97-SUMO1 [nucleoplasm] (R-HSA-3899298) K1020-EP300-G97-SUMO1 [nucleoplasm] (R-HSA-3899290) CTBP1-G97-SUMO1 [nucleoplasm] (R-HSA-3730764) K231-SAFB-G97-SUMO1 [nucleoplasm] (R-HSA-4085364) K294-SAFB-G97-SUMO1 [nucleoplasm] (R-HSA-4085341) K624-MKL1-G97-SUMO1 [nucleoplasm] (R-HSA-3900128) K576-MKL1-G97-SUMO1 [nucleoplasm] (R-HSA-3900225) K499-MKL1-G97-SUMO1 [nucleoplasm] (R-HSA-3900219) K631-DAXX-G97-SUMO1 [nucleoplasm] (R-HSA-4086044) K630-DAXX-G97-SUMO1 [nucleoplasm] (R-HSA-4086012) SIN3A-G97-SUMO1 [nucleoplasm] (R-HSA-4086058) PPARGC1A-G97-SUMO1 [nucleoplasm] (R-HSA-3903014) HIPK2-G97-SUMO1 [nucleoplasm] (R-HSA-4090362) K774-NCOA1-G97-SUMO1 [nucleoplasm] (R-HSA-4085292) K732-NCOA1-G97-SUMO1 [nucleoplasm] (R-HSA-4085278) K538-MBD1-G97-SUMO1 [nucleoplasm] (R-HSA-4090416) K499-MBD1-G97-SUMO1 [nucleoplasm] (R-HSA-4090332) ZNF131-G97-SUMO1 [nucleoplasm] (R-HSA-3730875) K90-NFKB2-G97-SUMO1 [cytosol] (R-HSA-4755511) K689-NFKB2-G97-SUMO1 [cytosol] (R-HSA-4755446) K863-NFKB2-G97-SUMO1 [cytosol] (R-HSA-4755412) K298-NFKB2-G97-SUMO1 [cytosol] (R-HSA-4755505) UBE2I-G97-SUMO1 [cytosol] (R-HSA-4656941) p-S172-IKBKE-G97-SUMO1 [nucleoplasm] (R-HSA-4755408) K309-IKBKG-G97-SUMO1 [nucleoplasm] (R-HSA-4755404) K277-IKBKG-G97-SUMO1 [nucleoplasm] (R-HSA-4755531) NFKBIA-G97-SUMO1 [nucleoplasm] (R-HSA-4656987) RANGAP1-G97-SUMO1 [nucleoplasm] (R-HSA-3730796) AURKA-G97-SUMO1 [cytosol] (R-HSA-4655413) TOP2B-G97-SUMO1 [nucleoplasm] (R-HSA-4641311) TOP1-G97-SUMO1 [nucleoplasm] (R-HSA-4641306) TOP2A-G97-SUMO1 [nucleoplasm] (R-HSA-4641341) K254-PCNA-G97-SUMO1 [nucleoplasm] (R-HSA-4615853) K-PCNA-G97-SUMO1 [nucleoplasm] (R-HSA-4615836) K164-PCNA-G97-SUMO1 [nucleoplasm] (R-HSA-4615951) MDC1-G97-SUMO1 [nucleoplasm] (R-HSA-4570527) STAG2-G97-SUMO1 [nucleoplasm] (R-HSA-3826645) RAD21-G97-SUMO1 [nucleoplasm] (R-HSA-3826574) K411-RAD52-G97-SUMO1 [nucleoplasm] (R-HSA-4568857) K412-RAD52-G97-SUMO1 [nucleoplasm] (R-HSA-4568850) K414-RAD52-G97-SUMO1 [nucleoplasm] (R-HSA-4568900) XRCC4-G97-SUMO1 [nucleoplasm] (R-HSA-4568869) K160-PML-G97-SUMO1 [nucleoplasm] (R-HSA-3730884) K490-PML-G97-SUMO1 [nucleoplasm] (R-HSA-3730833) K65-PML-G97-SUMO1 [nucleoplasm] (R-HSA-3730879) K203-PARP1-G97-SUMO1 [nucleoplasm] (R-HSA-4551625) K486-PARP1-G97-SUMO1 [nucleoplasm] (R-HSA-4551748) K496-WRN-G97-SUMO1 [nucleoplasm] (R-HSA-4568906) K898-WRN-G97-SUMO1 [nucleoplasm] (R-HSA-4568893) K356-WRN-G97-SUMO1 [nucleoplasm] (R-HSA-4568845) RNF168-SUMO1 [nucleoplasm] (R-HSA-4551631) XPC-G97-SUMO1 [nucleoplasm] (R-HSA-4570452) TDG-G97-SUMO1 [nucleoplasm] (R-HSA-4551682) SP100-G97-SUMO1 [nucleoplasm] (R-HSA-3730794) BRCA1-G97-SUMO1 [nucleoplasm] (R-HSA-3730735) RXRA-G97-SUMO1 [nucleoplasm] (R-HSA-4341090) NR5A2-G97-SUMO1 [nucleoplasm] (R-HSA-4755424) K386-AR-G97-SUMO1 [nucleoplasm] (R-HSA-4090321) K520-AR-G97-SUMO1 [nucleoplasm] (R-HSA-4090352) K293-NR3C1-G97-SUMO1 [nucleoplasm] (R-HSA-4341110) K277-NR3C1-G97-SUMO1 [nucleoplasm] (R-HSA-4341057) K389-THRA-G97-SUMO1 [nucleoplasm] (R-HSA-4719415) K283-THRA-G97-SUMO1 [nucleoplasm] (R-HSA-4719434) K399-NR3C2-G97-SUMO1 [nucleoplasm] (R-HSA-4341020) K428-NR3C2-G97-SUMO1 [nucleoplasm] (R-HSA-4341035) K494-NR3C2-G97-SUMO1 [nucleoplasm] (R-HSA-4341093) K89-NR3C2-G97-SUMO1 [nucleoplasm] (R-HSA-4341058) K119-NR5A1-G97-SUMO1 [nucleoplasm] (R-HSA-4546379) K194-NR5A1-G97-SUMO1 [nucleoplasm] (R-HSA-4546380) NR2C1-G97-SUMO1 [nucleoplasm] (R-HSA-4717492) K303-ESR1-G97-SUMO1 [nucleoplasm] (R-HSA-4090373) K266-ESR1-G97-SUMO1 [nucleoplasm] (R-HSA-4090359) K302-ESR1-G97-SUMO1 [nucleoplasm] (R-HSA-4090363) K299-ESR1-G97-SUMO1 [nucleoplasm] (R-HSA-4090349) K268-ESR1-G97-SUMO1 [nucleoplasm] (R-HSA-4090414) K531-PGR-G97-SUMO1 [nucleoplasm] (R-HSA-4341021) K7-PGR-G97-SUMO1 [nucleoplasm] (R-HSA-4341052) K388-PGR-G97-SUMO1 [nucleoplasm] (R-HSA-4341056) K132-NR1H4-G97-SUMO1 [nucleoplasm] (R-HSA-9610527) NR1H4-G97-SUMO1 [nucleoplasm] (R-HSA-4755434) PPARG-G97-SUMO1 [nucleoplasm] (R-HSA-4717445) K395-PPARG-G97-SUMO1 [nucleoplasm] (R-HSA-4717446) PPARA-G97-SUMO1 [nucleoplasm] (R-HSA-4341069) K443-THRB-G97-SUMO1 [nucleoplasm] (R-HSA-4719431) K146-THRB-G97-SUMO1 [nucleoplasm] (R-HSA-4719410) K50-THRB-G97-SUMO1 [nucleoplasm] (R-HSA-4719401) RORA-G97-SUMO1 [nucleoplasm] (R-HSA-4719426) HIC1-G97-SUMO1 [nucleoplasm] (R-HSA-4570544) TP53BP1-G97-SUMO1 [nucleoplasm] (R-HSA-3730731) SP3-G97-SUMO1 [nucleoplasm] (R-HSA-3730646) K423-MITF-G97-SUMO1 [nucleoplasm] (R-HSA-3730755) K289-MITF-G97-SUMO1 [nucleoplasm] (R-HSA-3730738) K25-FOXL2-G97-SUMO1 [nucleoplasm] (R-HSA-3968400) K150-FOXL2-G97-SUMO1 [nucleoplasm] (R-HSA-3968382) K114-FOXL2-G97-SUMO1 [nucleoplasm] (R-HSA-3968396) HNRNPC-G97-SUMO1 [nucleoplasm] (R-HSA-4570515) K497-NOP58-G97-SUMO1 [nucleoplasm] (R-HSA-4570504) K467-NOP58-G97-SUMO1 [nucleoplasm] (R-HSA-4570462) DNMT3B-G97-SUMO1 [nucleoplasm] (R-HSA-4655444) DNMT3A-G97-SUMO1 [nucleoplasm] (R-HSA-4655383) DNMT1-G97-SUMO1 [nucleoplasm] (R-HSA-4655358) K84-CBX5-G97-SUMO1 [nucleoplasm] (R-HSA-4615838) K-CBX5-G97-SUMO1 [nucleoplasm] (R-HSA-4615955) K476-HDAC1-G97-SUMO1 [nucleoplasm] (R-HSA-4615867) K444-HDAC1-G97-SUMO1 [nucleoplasm] (R-HSA-4616028) CBX4-G97-SUMO1 [nucleoplasm] (R-HSA-4551756) HDAC2-G97-SUMO1 [nucleoplasm] (R-HSA-4616032) SUZ12-G97-SUMO1 [nucleoplasm] (R-HSA-4615961) SATB1-G97-SUMO1 [nucleoplasm] (R-HSA-4615877) HDAC4-G97-SUMO1 [nucleoplasm] (R-HSA-4615956) K1971-CHD3-G97-SUMO1 [nucleoplasm] (R-HSA-8956370) HIST1H4-G97-SUMO1 [nucleoplasm] (R-HSA-4570549) BMI1-G97-SUMO1 [nucleoplasm] (R-HSA-4551654) TFAP2B-G97-SUMO1 [nucleoplasm] (R-HSA-3730839) TFAP2C-G97-SUMO1 [nucleoplasm] (R-HSA-3730823) TFAP2A-1-G97-SUMO1 [nucleoplasm] (R-HSA-3730825) SUMO1(2-101) [nucleoplasm] (R-HSA-2990831) SUMO1 [nucleoplasm] (R-HSA-877304) UBA2-G97-SUMO1 [nucleoplasm] (R-HSA-3730616) UBE2I-G97-SUMO1 [nucleoplasm] (R-HSA-3730622) HERC2-SUMO1 [nucleoplasm] (R-HSA-4551761)	0.544	2