An unknown protease degrades ACACB

Stable Identifier
R-HSA-4167501
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol, mitochondrial outer membrane
ReviewStatus
5/5
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An unknown protease degrades ACACB
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Cytosolic acetyl-CoA carboxylases 1 and 2 (Btn-ACACA/B:2Mn2+) are degraded proteolytically to biocytin (BCTN aka biotinyl-lysine) or small biotinyl peptides (not shown here) by an unknown protease (Chandler & Ballard 1985, Hymes & Wolf 1996, Hymes & Wolf 1999).
Literature References
PubMed ID Title Journal Year
8930409 Biotinidase and its roles in biotin metabolism

Hymes, J, Wolf, B

Clin. Chim. Acta 1996
2868710 Distribution and degradation of biotin-containing carboxylases in human cell lines

Ballard, FJ, Chandler, CS

Biochem. J. 1985
10064314 Human biotinidase isn't just for recycling biotin

Hymes, J, Wolf, B

J. Nutr. 1999
Participants
Input
Output
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as an event of
Catalyst Activity

peptidase activity of unknown peptidase [cytosol]

Physical Entity
unknown peptidase [cytosol] (Homo sapiens)
Activity
peptidase activity (GO:0008233)
Authored
Jassal, B  (2013-02-06)
Reviewed
D'Eustachio, P  (2013-04-15)
Created
Jassal, B  (2013-08-15)
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