P2Y6 receptor can bind to UDP

Stable Identifier
R-HSA-417896
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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The P2Y6 receptor (Communi D et al, 1996) is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. Four transcript variants encoding the same isoform have been identified for this gene. The effects of P2Y6 are mediated by coupling to stimulation of both the phosphoinositide and adenylyl cyclase pathways, a unique feature among the P2Y family (Communi D et al,1997).

Literature References
PubMed ID Title Journal Year
8670200 Cloning, functional expression and tissue distribution of the human P2Y6 receptor

Communi, D, Parmentier, M, Boeynaems, JM

Biochem Biophys Res Commun 1996
9405388 Cloning of a human purinergic P2Y receptor coupled to phospholipase C and adenylyl cyclase

Communi, D, Govaerts, C, Parmentier, M, Boeynaems, JM

J Biol Chem 1997
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