ATP2B1-4 transport cytosolic Ca2+ to extracellular region

Stable Identifier
R-HSA-418309
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
PMCA extrusion of Ca2+
Locations in the PathwayBrowser
General
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The plasma membrane Ca-ATPases 1-4 (ATP2B1-4, PMCAs) are P-type Ca2+-ATPases regulated by calmodulin. The PMCA also counter-transports a proton. PMCA is important for Ca2+ homeostasis and function.

Literature References
PubMed ID Title Journal Year
2844759 Complete primary structure of a human plasma membrane Ca2+ pump

Verma, AK, Filoteo, AG, Stanford, DR, Wieben, ED, Penniston, JT, Strehler, EE, Fischer, R, Heim, R, Vogel, G, Mathews, S

J Biol Chem 1988
5961668 ATP-dependent Ca++-extrusion from human red cells

Schatzmann, HJ

Experientia 1966
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
calcium-transporting ATPase activity of ATP2B1-4 [plasma membrane]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created