Reactome: A Curated Pathway Database

ATP2B1-4 transport cytosolic Ca2+ to extracellular region

Stable Identifier
R-HSA-418309
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
PMCA extrusion of Ca2+
Locations in the PathwayBrowser
Summation

The plasma membrane Ca-ATPases 1-4 (ATP2B1-4, PMCAs) are P-type Ca2+-ATPases regulated by calmodulin. The PMCA also counter-transports a proton. PMCA is important for Ca2+ homeostasis and function.

Literature References
PubMed ID Title Journal Year
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
calcium-transporting ATPase activity of ATP2B1-4 [plasma membrane] ATP2B1-4 [plasma membrane] calcium-transporting ATPase activity (0005388)
Orthologous Events
Cross References
Rhea