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MLLT4-2 [cytosol]
Stable Identifier
R-HSA-418342
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Afadin, AFAD_HUMAN, MLLT4 isoform 2
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Homo sapiens)
Cell junction organization (Homo sapiens)
Cell-cell junction organization (Homo sapiens)
Adherens junctions interactions (Homo sapiens)
Interaction of Afadin with F-actin (Homo sapiens)
Afadin:F-actin [cytosol] (Homo sapiens)
MLLT4-2 [cytosol] (Homo sapiens)
MLLT4-2 [cytosol] (Homo sapiens)
Interaction of Nectins with Afadin (Homo sapiens)
MLLT4-2 [cytosol] (Homo sapiens)
Nectin:afadin [plasma membrane] (Homo sapiens)
MLLT4-2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P55196-2 AFDN
Gene Names
AFDN, AF6, MLLT4
Other Identifiers
11734163_a_at
11743232_a_at
11743634_s_at
11755183_a_at
11756122_s_at
11757074_s_at
11757648_a_at
17014714
208512_PM_s_at
208512_s_at
214939_PM_x_at
214939_x_at
224685_PM_at
224685_at
230622_PM_at
230622_at
238871_PM_at
238871_at
2936858
2936859
2936864
2936866
2936867
2936868
2936869
2936872
2936873
2936874
2936875
2936876
2936877
2936880
2936883
2936884
2936887
2936889
2936892
2936893
2936894
2936895
2936902
2936903
2936904
2936905
2936906
2936911
2936915
2936926
2936927
2936928
2936930
2936932
2936933
2936934
2936935
2936936
2936937
2936941
2936947
2936948
2936949
2936950
2936951
2936952
2936953
2936954
2936961
2936962
2936963
2936964
2936965
2936966
2936967
2936968
4048361
4048364
4048397
4048399
4048401
4048403
4048405
4048407
4048409
41105_s_at
4301
58844_s_at
65981_at
80948_at
8123407
82598_at
A_14_P110552
A_23_P256603
A_23_P436353
A_33_P3233105
A_33_P3278407
A_33_P3278410
GE56854
GE81579
GE85382
GE85388
GO:0005515
GO:0005634
GO:0005654
GO:0005829
GO:0005886
GO:0005911
GO:0005912
GO:0007155
GO:0007165
GO:0007267
GO:0008092
GO:0010628
GO:0016607
GO:0022409
GO:0023052
GO:0030054
GO:0030154
GO:0030336
GO:0031267
GO:0032880
GO:0034330
GO:0043226
GO:0044291
GO:0044331
GO:0045296
GO:0046930
GO:0046931
GO:0048856
GO:0048870
GO:0050839
GO:0051015
GO:0061951
GO:0065003
GO:0070160
GO:0070161
GO:0070830
GO:0072659
GO:0090557
GO:2000049
HMNXSV003030974
HMNXSV003037447
Hs.100469.2.S1_3p_at
Hs.100469.6.S1_3p_a_at
Hs.113849.0.A1_3p_at
Hs.144019.0.A1_3p_at
ILMN_1651310
PH_hs_0005607
RNA95072|RNS_154_193
TC06001184.hg
g5174574_3p_a_at
p33827
Participates
as a component of
Nectin:afadin [plasma membrane] (Homo sapiens)
Afadin:F-actin [cytosol] (Homo sapiens)
as an input of
Interaction of Nectins with Afadin (Homo sapiens)
Interaction of Afadin with F-actin (Homo sapiens)
Inferred To
afd-1 [cytosol]
(Caenorhabditis elegans)
Afdn [cytosol]
(Mus musculus)
Afdn [cytosol]
(Rattus norvegicus)
AFDN [cytosol]
(Bos taurus)
AFDN [cytosol]
(Canis familiaris)
AFDN [cytosol]
(Sus scrofa)
MLLT4-2 [cytosol]
(Gallus gallus)
cno [cytosol]
(Drosophila melanogaster)
Cross References
RefSeq
NP_001193937.1
,
XP_005267053.1
,
NP_001278893.1
,
NP_001035089.1
OpenTargets
ENSG00000130396
GeneCards
P55196
HPA
ENSG00000130396-AFDN
Ensembl
ENSP00000375956
,
ENSP00000375960
,
ENST00000392108
,
ENSP00000383623
,
ENSP00000404595
,
ENSG00000130396
,
ENST00000447894
,
ENST00000400822
,
ENST00000392112
PRO
P55196
Pharos - Targets
P55196
PDB
2AIN
,
1XZ9
,
5A6C
,
1T2M
,
2EXG
,
7QCR
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P12931 SRC
6
p-Y419-SRC [nucleoplasm]
(R-HSA-8937690)
SRC [cytosol]
(R-HSA-9628701)
p-Y419-SRC [cytosol]
(R-HSA-8964276)
MyrG-SRC [plasma membrane]
(R-HSA-8876922)
MyrG,p-Y530-SRC [plasma membrane]
(R-HSA-377598)
MyrG-p-Y419-SRC [plasma membrane]
(R-HSA-1810408)
0.65
7
UniProt:Q9NQS3 NECTIN3
1
PVRL3 [plasma membrane]
(R-HSA-449762)
0.646
4
UniProt:P31946 YWHAB
1
YWHAB [cytosol]
(R-HSA-48888)
0.604
4
UniProt:P63104 YWHAZ
2
YWHAZ [nucleoplasm]
(R-HSA-450469)
YWHAZ [cytosol]
(R-HSA-206099)
0.536
2
UniProt:P19320 VCAM1
1
VCAM1 [plasma membrane]
(R-HSA-197834)
0.527
4
UniProt:Q92692 NECTIN2
1
PVRL2 [plasma membrane]
(R-HSA-419006)
0.499
2
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