Gq activation by P2Y purinoceptor 1

Stable Identifier
R-HSA-418579
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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Gq activation by P2Y purinoceptor 1
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The G-protein alpha subunit exchanges GDP for GTP
Literature References
PubMed ID Title Journal Year
14742685 Agonist binding and Gq-stimulating activities of the purified human P2Y1 receptor

Waldo, GL, Harden, TK

Mol Pharmacol 2004
Participants
Input
Output
Participates
as an event of
Catalyst Activity

guanyl-nucleotide exchange factor activity of ADP:P2RY1:G-protein Gq/11 (inactive) [plasma membrane]

Physical Entity
ADP:P2RY1:G-protein Gq/11 (inactive) [plasma membrane] (Homo sapiens)
Activity
guanyl-nucleotide exchange factor activity (GO:0005085)
Inferred From
Activated human P2Y purinoceptor 1 binds mouse G-protein Gq (Homo sapiens)
Authored
Akkerman, JW  (2009-06-03)
Reviewed
Harper, MT  (2009-11-02)
Poole, AW  (2009-11-02)
Jones, ML  (2009-11-02)
Created
Jupe, S  (2009-04-24)
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