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CDH11 [plasma membrane]
Stable Identifier
R-HSA-418979
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Cadherin-11, CAD11_HUMAN
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Homo sapiens)
Cell junction organization (Homo sapiens)
Cell-cell junction organization (Homo sapiens)
Adherens junctions interactions (Homo sapiens)
Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin (Homo sapiens)
Cadherin trans-homodimer [cell junction] (Homo sapiens)
Classic Cadherin [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
Classic Cadherin [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin (Homo sapiens)
Cadherin:Catenin complex [plasma membrane] (Homo sapiens)
Classic Cadherin [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
Classic Cadherin [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
Regulation of Homotypic Cell-Cell Adhesion (Homo sapiens)
Regulation of Expression and Function of Type II Classical Cadherins (Homo sapiens)
Regulation of CDH11 Expression and Function (Homo sapiens)
Regulation of CDH11 function (Homo sapiens)
AMOT-2 binds CDH11 (Homo sapiens)
CDH11:CTNND1:CTNNB1 [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1:AMOT-2 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1 [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
ANGPTL4 binds CDH11 (Homo sapiens)
ANGPTL4(164-406):CDH11:CTNND1:CTNNB1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1 [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1 [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CDH11 associates with catenins (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1/JUP [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1 [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CDH11 homotypic and heterotypic interactions (Homo sapiens)
CDH11 forms heterotypic trans dimer with CDH24 (Homo sapiens)
CDH11:CTNDD1:CTNNB1/JUP:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1 [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
Heterotypic CDH11:CDH24 trans dimer [plasma membrane] (Homo sapiens)
CDH11:CTNDD1:CTNNB1/JUP:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1 [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CDH11 forms heterotypic trans dimer with CDH8 (Homo sapiens)
CDH11:CTNDD1:CTNNB1/JUP:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1 [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
Heterotypic CDH11:CDH8 trans dimer [plasma membrane] (Homo sapiens)
CDH11:CTNDD1:CTNNB1/JUP:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1 [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CDH11 forms homotypic trans dimer (Homo sapiens)
CDH11:CTNDD1:CTNNB1/JUP:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1 [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
Homotypic CDH11 trans dimer [plasma membrane] (Homo sapiens)
CDH11:CTNDD1:CTNNB1/JUP:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1 [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
trans-CDH11:CTNDD1:CTNNB1/JUP:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1 [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
trans-CDH11:CTNDD1:CTNNB1/JUP:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1 [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CTNNA1 binds to CDH11-bound CTNNB1 (Homo sapiens)
CDH11:CTNDD1:CTNNB1/JUP:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1 [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP:CTNNA1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1/JUP [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1 [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
CTNNB1 dissociates from CDH11 upon ANGPTL4 binding (Homo sapiens)
ANGPTL4(164-406):CDH11:CTNND1 [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
ANGPTL4(164-406):CDH11:CTNND1:CTNNB1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1 [plasma membrane] (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
Membrane-bound CDH11 is cleaved to produce secreted CDH11 isoform (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
Regulation of CDH11 mRNA translation by microRNAs (Homo sapiens)
CDH11 canonical mRNA is translated into CDH11 canonical protein isoform (Homo sapiens)
CDH11 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P55287 CDH11
Gene Names
CDH11
Chain
signal peptide:1-22, propeptide:23-53, chain:54-796
Reference Genes
BioGPS Gene:1009 CDH11
COSMIC (genes):CDH11 CDH11
CTD Gene:1009 CDH11
dbSNP Gene:1009 CDH11
ENSEMBL:ENSG00000140937 CDH11
ENSEMBL_homo_sapiens_GENE:ENSG00000140937.14 CDH11
HGNC:1750 CDH11
KEGG Gene (Homo sapiens):1009 CDH11
Monarch:1009 CDH11
NCBI Gene:1009 CDH11
OMIM:600023 CDH11
UCSC:P55287 CDH11
Reference Transcript
RefSeq:XM_005255763.2 CDH11
RefSeq:XM_005255762.2 CDH11
RefSeq:XM_005255761.3 CDH11
RefSeq:NM_001797.3 CDH11
RefSeq:NM_001308392.1 CDH11
RefSeq:XM_011522803.2 CDH11
Other Identifiers
1009
11742873_a_at
11749461_a_at
11753109_a_at
11759412_at
11759413_s_at
16827041
207172_PM_s_at
207172_s_at
207173_PM_x_at
207173_x_at
2087_s_at
236179_PM_at
236179_at
239286_PM_at
239286_at
3694658
3694659
3694660
3694661
3694662
3694663
3694664
3694665
3694666
3694667
3694668
3694676
3694677
3694679
3694684
3694691
3694693
3694694
3694697
3694698
3694702
3694703
3694704
3694705
3694706
3694727
3694728
3694754
3694755
36976_at
58058_at
8001800
82858_at
A_23_P152305
A_24_P253676
A_33_P3232193
D21255_at
GE57113
GO:0000902
GO:0001501
GO:0001503
GO:0003189
GO:0005509
GO:0005576
GO:0005615
GO:0005737
GO:0005886
GO:0005912
GO:0007043
GO:0007155
GO:0007156
GO:0016020
GO:0016339
GO:0016342
GO:0016477
GO:0021957
GO:0023052
GO:0030154
GO:0030336
GO:0034330
GO:0034332
GO:0043226
GO:0044331
GO:0045202
GO:0045296
GO:0046872
GO:0048041
GO:0048856
GO:0048870
GO:0050804
GO:0070062
GO:0098609
GO:0098685
GO:0098978
HMNXSV003027736
HMNXSV003027894
HMNXSV003029183
Hs.103316.0.A1_3p_at
Hs.145968.0.A1_3p_at
ILMN_1672611
PH_hs_0025900
TC16001165.hg
g4502716_3p_a_at
g575577_3p_a_at
Participates
as a member of
Classic Cadherin [plasma membrane] (Homo sapiens)
as a component of
ANGPTL4(164-406):CDH11:CTNND1 [plasma membrane] (Homo sapiens)
CDH11:Ctnnd1:Ctnnb1 [plasma membrane] (Homo sapiens)
CDH11:CTNND1:JUP [plasma membrane] (Homo sapiens)
CDH11:CTNND1:CTNNB1 [plasma membrane] (Homo sapiens)
as an input of
Membrane-bound CDH11 is cleaved to produce secreted CDH11 isoform (Homo sapiens)
CDH11 associates with catenins (Homo sapiens)
as an output of
CDH11 canonical mRNA is translated into CDH11 canonical protein isoform (Homo sapiens)
Other forms of this molecule
CDH11(54-?) [extracellular region]
CDH11(?-796) [plasma membrane]
Inferred To
CDH11 [plasma membrane]
(Bos taurus)
CDH11 [plasma membrane]
(Canis familiaris)
CDH11 [plasma membrane]
(Gallus gallus)
CDH11 [plasma membrane]
(Sus scrofa)
cdh11 [plasma membrane]
(Danio rerio)
cdh11 [plasma membrane]
(Xenopus tropicalis)
CadN2 [plasma membrane]
(Drosophila melanogaster)
Cdh11 [plasma membrane]
(Mus musculus)
Cdh11 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_001788.2
,
XP_005255819.1
,
XP_005255818.1
,
XP_005255820.1
,
XP_011521105.1
,
NP_001295321.1
OpenTargets
ENSG00000140937
GeneCards
P55287
HPA
ENSG00000140937-CDH11
Ensembl
ENSG00000140937
,
ENST00000394156
,
ENSP00000268603
,
ENSP00000377711
,
ENST00000268603
PRO
P55287
Pharos - Targets
P55287
Orphanet
26055
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