Binding of ATP to P2X receptors

Stable Identifier
R-HSA-419490
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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P2X receptors are a family of cation-permeable ligand gated ion channels that open in response to the binding of extracellular adenosine triphosphate (ATP) (Gicquel et al. 2015). All members of the family are thought to be functionally trimeric.

Literature References
PubMed ID Title Journal Year
12907444 Lack of evidence for functional ADP-activated human P2X1 receptors supports a role for ATP during hemostasis and thrombosis

Vial, C, Pitt, SJ, Roberts, J, Rolf, MG, Mahaut-Smith, MP, Evans, RJ

Blood 2003
10228183 Single channel properties of P2X2 purinoceptors

Ding, S, Sachs, F

J. Gen. Physiol. 1999
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