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p-Y-PLXNB1 [plasma membrane]
Stable Identifier
R-HSA-419609
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
phosphorylated Plexin B1
Icon
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
Semaphorin interactions (Homo sapiens)
Sema4D in semaphorin signaling (Homo sapiens)
Sema4D induced cell migration and growth-cone collapse (Homo sapiens)
Activation of Rho by LARG and PDZ-RhoGEF (Homo sapiens)
SEMA4D:ERBB2:p-Y-PLXNB1:RND1:ARHGEF11,ARHGEF12 [plasma membrane] (Homo sapiens)
SEMA4D:ERBB2:p-Y-PLXNB1:RND1 [plasma membrane] (Homo sapiens)
SEMA4D:ERBB2:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
ERBB2:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
LARG and PDZ-RhoGEF binds to Plexin-B1 (Homo sapiens)
SEMA4D:ERBB2:p-Y-PLXNB1:RND1 [plasma membrane] (Homo sapiens)
SEMA4D:ERBB2:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
ERBB2:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
SEMA4D:ERBB2:p-Y-PLXNB1:RND1:ARHGEF11,ARHGEF12 [plasma membrane] (Homo sapiens)
SEMA4D:ERBB2:p-Y-PLXNB1:RND1 [plasma membrane] (Homo sapiens)
SEMA4D:ERBB2:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
ERBB2:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
SEMA4D interacts with Plexin-B1:ErbB2 (Homo sapiens)
SEMA4D:ERBB2:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
ERBB2:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
Sema4D mediated inhibition of cell attachment and migration (Homo sapiens)
Active Rac1 interacts with Plexin-B1:Sema4D (Homo sapiens)
SEMA4D:MET:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
MET:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
Sema4D:pPlexin-B1:Met:RAC1-GTP [plasma membrane] (Homo sapiens)
SEMA4D:MET:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
MET:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity (Homo sapiens)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Homo sapiens)
SEMA4D:MET:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
MET:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
Inactivation of Rho-GTP by p190RhoGAP (Homo sapiens)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP:ARHGAP35 [plasma membrane] (Homo sapiens)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Homo sapiens)
SEMA4D:MET:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
MET:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
Rnd1 interacts with Plexin-B1:Sema4D (Homo sapiens)
SEMA4D:MET:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
MET:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Homo sapiens)
SEMA4D:MET:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
MET:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
SEMA4D interacts with Plexin-B1:Met (Homo sapiens)
SEMA4D:MET:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
MET:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
p190RhoGAP binds Plexin-B1 (Homo sapiens)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Homo sapiens)
SEMA4D:MET:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
MET:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP:ARHGAP35 [plasma membrane] (Homo sapiens)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Homo sapiens)
SEMA4D:MET:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
MET:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O43157 PLXNB1
Gene Names
PLXNB1, KIAA0407, PLXN5, SEP
Chain
signal peptide:1-19, chain:20-2135
Reference Genes
COSMIC (genes):PLXNB1 PLXNB1
dbSNP Gene:5364 PLXNB1
ENSEMBL:ENSG00000164050 PLXNB1
Participates
as a component of
MET:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
ERBB2:p-Y-PLXNB1 [plasma membrane] (Homo sapiens)
Other forms of this molecule
PLXNB1 [plasma membrane]
Inferred To
phospho-PLXNB1 [plasma membrane]
(Bos taurus)
phospho-PLXNB1 [plasma membrane]
(Canis familiaris)
phospho-PLXNB1 [plasma membrane]
(Sus scrofa)
phospho-p-Y-PLXNB1 [plasma membrane]
(Gallus gallus)
phospho-plxnb1b [plasma membrane]
(Danio rerio)
phospho-PlexB [plasma membrane]
(Drosophila melanogaster)
phospho-Plxnb1 [plasma membrane]
(Mus musculus)
phospho-Plxnb1 [plasma membrane]
(Rattus norvegicus)
phospho-plxnb1 [plasma membrane]
(Xenopus tropicalis)
phospho-plx-2 [plasma membrane]
(Caenorhabditis elegans)
Modified Residues
Name
O4'-phospho-L-tyrosine at unknown position
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P08581 MET
7
p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
(R-HSA-6806973)
MET [plasma membrane]
(R-HSA-419603)
p-Y1003,4Y-MET [plasma membrane]
(R-HSA-8874689)
p-Y1234,Y1235,Y1356-MET [plasma membrane]
(R-HSA-6807014)
MonoUb-K,p-Y1003,4Y-MET [plasma membrane]
(R-HSA-8875180)
MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane]
(R-HSA-8875181)
p-Y1349,Y1356-MET [plasma membrane]
(R-HSA-6807032)
0.775
9
UniProt:Q92730 RND1
1
RND1 [plasma membrane]
(R-HSA-396949)
0.775
5
UniProt:P61587 RND3
1
RND3 [plasma membrane]
(R-HSA-9696265)
0.676
3
UniProt:P52198 RND2
1
RND2 [plasma membrane]
(R-HSA-9696269)
0.558
2
UniProt:Q04912 MST1R
3
p-Y1238,1239,1353,1360-MST1R (310-1400) [plasma membrane]
(R-HSA-8852533)
MST1R (25-304) [plasma membrane]
(R-HSA-6800303)
MST1R (310-1400) [plasma membrane]
(R-HSA-6800308)
0.524
3
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