Reactome | PATJ [plasma membrane]

PATJ [plasma membrane]

Stable Identifier

R-HSA-420011

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

INADL, InaD-like protein, INADL_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8NI35 PATJ

Gene Names

PATJ, CIPP, INADL

Chain

chain:1-1801

Reference Genes

BioGPS Gene:10207 PATJ

COSMIC (genes):PATJ PATJ

CTD Gene:10207 PATJ

dbSNP Gene:10207 PATJ

ENSEMBL:ENSG00000132849 PATJ

HGNC:28881 PATJ

Monarch:10207 PATJ

NCBI Gene:10207 PATJ

OMIM:603199 PATJ

UCSC:Q8NI35 PATJ

Reference Transcript

RefSeq:NM_176877.5 PATJ

Other Identifiers

10207

11733371_at

11745624_s_at

11751702_a_at

11760401_a_at

11760402_x_at

11760849_a_at

11760850_x_at

16665373

214493_3p_s_at

214493_PM_s_at

214493_s_at

214705_PM_at

214705_at

223681_PM_s_at

223681_s_at

232041_PM_at

232041_at

2339140

2339147

2339148

2339150

2339151

2339153

2339154

2339155

2339157

2339159

2339160

2339161

2339162

2339163

2339164

2339168

2339171

2339174

2339182

2339184

2339185

2339186

2339188

2339189

2339190

2339196

2339198

2339199

2339201

2339202

2339204

2339213

2339225

2339226

2339227

2339229

2339230

2339232

2339236

2339241

2339251

2339252

2339261

2339264

2339269

2339270

2339271

2339272

2339273

2339274

2339275

2339276

2339277

2339278

2339280

2339281

2339282

2339284

2339285

2339286

2339287

2339288

2339289

2339295

2339301

2339306

2339307

2339308

2339309

2339310

2339311

239173_PM_at

239173_at

240570_PM_at

240570_at

38145_at

56055_at

56141_at

69939_at

71139_at

7901804

86559_at

A_14_P103036

A_14_P105241

A_14_P122643

A_14_P123142

A_14_P128104

A_23_P126100

A_23_P321034

A_24_P274072

A_24_P942454

A_32_P88958

A_33_P3422429

GE55141

GE61591

GE63186

GO:0005515

GO:0005737

GO:0005829

GO:0005886

GO:0005923

GO:0007163

GO:0016020

GO:0016324

GO:0030054

GO:0034330

GO:0034451

GO:0035089

GO:0035556

GO:0043296

GO:0045177

GO:0045197

GO:0048471

GO:0070062

GO:0070160

GO:0070161

GO:0120192

HMNXSV003030507

HMNXSV003045277

HMNXSV003056798

Hs.211880.0.A1_3p_at

Hs.298807.0.A1_3p_at

Hs.313505.0.A1_3p_at

Hs.321197.1.A1_3p_a_at

Hs.321197.1.A1_3p_at

Hs.321197.1.A1_3p_x_at

Hs.321197.2.A1_3p_at

ILMN_1724666

ILMN_1747318

ILMN_1748984

ILMN_1773312

PH_hs_0025508

TC01000703.hg

g11933154_3p_s_at

Participates

as a component of

CRB3:PALS1:PATJ complex [plasma membrane] (Homo sapiens)

as an input of

Crumbs forms a ternary complex with Pals1 and PATJ at tight junctions (Homo sapiens)

Cross References

RefSeq

NP_795352.3

ENSEMBL

ENSP00000360200, ENST00000371158, ENSP00000433669, ENSG00000132849, ENST00000484937

OpenTargets

ENSG00000132849

GeneCards

PATJ

HPA

ENSG00000132849-PATJ

PRO

Q8NI35

Pharos - Targets

Q8NI35

GlyGen

Q8NI35

PDB

1VF6, 2DB5, 4Q2N, 2DMZ, 2DAZ, 2EHR, 2DLU, 6IRD, 2DM8, 2D92

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8N3R9 PALS1	2	MPP5 [plasma membrane] (R-HSA-419969) MPP5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-9689606)	0.784	6
UniProt:P46937 YAP1	8	YAP1 [cytosol] (R-HSA-1253345) YAP1 [nucleoplasm] (R-HSA-1253322) p-5S-YAP1 [cytosol] (R-HSA-2028554) p-S127-YAP1 [cytosol] (R-HSA-2028553) p-Y-YAP1 [nucleoplasm] (R-HSA-8937857) p-Y-YAP1 [cytosol] (R-HSA-8937843) p-Y407-YAP1 [nucleoplasm] (R-HSA-8956661) p-Y407-YAP1 [cytosol] (R-HSA-9865208)	0.713	9
UniProt:O95049 ZO3			0.684	5
UniProt:Q99569 PKP4	2	PKP4 [plasma membrane] (R-HSA-6814401) PKP4 [cornified envelope] (R-HSA-8847721)	0.623	3
UniProt:Q9C0D5 TANC1			0.623	2
UniProt:O95832 CLDN1	3	CLDN1 [endosome membrane] (R-HSA-9946308) CLDN1 [plasma membrane] (R-HSA-419999) CLDN1 [cell junction] (R-HSA-421238)	0.609	2
UniProt:P17252 PRKCA	8	PRKCA [cytosol] (R-HSA-58196) p-T497,T638,S657-PRKCA [cytosol] (R-HSA-4332337) p-T497-PRKCA [cytosol] (R-HSA-5218731) pT497,T638,S657-PRKCA [plasma membrane] (R-HSA-4332340) PRKCA [plasma membrane] (R-HSA-156469) p-T497,T638,S657-PRKCA [nucleoplasm] (R-HSA-5223292) PRKCA [photoreceptor disc membrane] (R-HSA-2648987) PRKCA [nucleoplasm] (R-HSA-450530)	0.554	2
UniProt:P60484 PTEN	20	K48polyUb-PTEN [cytosol] (R-HSA-8874327) PolyUb-PTEN [nucleoplasm] (R-HSA-6782515) PTEN H93R [cytosol] (R-HSA-2318524) PTEN C124R [cytosol] (R-HSA-2317439) PTEN H93Y [cytosol] (R-HSA-2318520) PTEN R130G [cytosol] (R-HSA-2317339) PTEN H93D [cytosol] (R-HSA-2318550) PTEN R130L [cytosol] (R-HSA-2317430) PTEN H93A [cytosol] (R-HSA-2318544) PTEN G129E [cytosol] (R-HSA-2318509) PTEN S170N [cytosol] (R-HSA-2318408) PTEN R173P [cytosol] (R-HSA-2317480) PTEN R130Q [cytosol] (R-HSA-2317416) PTEN H93Q [cytosol] (R-HSA-2318565) PTEN G129R [cytosol] (R-HSA-2318501) PTEN H123Y [cytosol] (R-HSA-2318469) PTEN S170R [cytosol] (R-HSA-2318437) PTEN R173C [cytosol] (R-HSA-2317478) PTEN R173H [cytosol] (R-HSA-2317473) PTEN C124S [cytosol] (R-HSA-2317379)	0.544	3
UniProt:P82279 CRUM1			0.499	2
UniProt:P35240 NF2	1	NF2 [plasma membrane] (R-HSA-5669168)	0.499	2
UniProt:O00254 F2RL2	3	F2RL2(22-38) [extracellular region] (R-HSA-114588) F2RL2(22-374) [plasma membrane] (R-HSA-61313) F2RL2 [plasma membrane] (R-HSA-114532)	0.463	2