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SCT [extracellular region]
Stable Identifier
R-HSA-420060
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Secretin, SECR_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
SCTR:SCT [plasma membrane] (Homo sapiens)
SCT [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
SCTR:SCT [plasma membrane] (Homo sapiens)
SCT [extracellular region] (Homo sapiens)
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
SCTR:SCT [plasma membrane] (Homo sapiens)
SCT [extracellular region] (Homo sapiens)
Ligands of GPCRs that activate Gs [extracellular region] (Homo sapiens)
SCT [extracellular region] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class B/2 (Secretin family receptors) (Homo sapiens)
Glucagon-type ligand receptors (Homo sapiens)
Secretin receptor binds secretin (Homo sapiens)
SCT [extracellular region] (Homo sapiens)
SCTR:SCT [plasma membrane] (Homo sapiens)
SCT [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P09683 SCT
Gene Names
SCT
Chain
signal peptide:1-18, propeptide:19-26, peptide:28-54, propeptide:58-121
Reference Genes
BioGPS Gene:6343 SCT
COSMIC (genes):SCT SCT
CTD Gene:6343 SCT
dbSNP Gene:6343 SCT
ENSEMBL:ENSG00000070031 SCT
ENSEMBL:ENSG00000274473 SCT
HGNC:10607 SCT
KEGG Gene (Homo sapiens):6343 SCT
Monarch:6343 SCT
NCBI Gene:6343 SCT
OMIM:182099 SCT
UCSC:P09683 SCT
Reference Transcript
RefSeq:NM_021920.3 SCT
Other Identifiers
0004570170
11742661_at
16734040
221198_at
3358240
3358242
3358243
3358244
3358245
3358246
3358247
50961
6343
7945498
A_23_P104594
AAG31443
AF244355
CCDS7709
ENSG00000070031
ENSG00000274473
ENSP00000176195
ENSP00000483559
ENST00000176195
ENST00000176195.3
ENST00000622382
EntrezGene:6343
EntrezGene:SCT
g12545379_3p_at
GO:0001664
GO:0002024
GO:0003674
GO:0005102
GO:0005179
GO:0005575
GO:0005576
GO:0005615
GO:0005623
GO:0006629
GO:0006810
GO:0007165
GO:0007186
GO:0007267
GO:0007420
GO:0008150
GO:0009056
GO:0009790
GO:0009992
GO:0021766
GO:0030157
GO:0031667
GO:0032098
GO:0043950
GO:0046659
GO:0047485
GO:0048167
GO:0048566
GO:0048856
GO:0050996
GO:0090187
GO:0090274
GO:1903640
HGNC:10607
HPA050961
ILMN_1705763
IPR000532
IPR015675
MIM:182099
NM_021920
NP_068739
PF00123
PH_hs_0029684
SCT
SCT-201
SCT-202
SM00070
TC11001243.hg
UPI00001357C7
Participant Of
input
Secretin receptor binds secretin
hasMember
Ligands of GPCRs that activate Gs [extracellular region]
hasComponent
SCTR:SCT [plasma membrane]
Inferred To
SCT [extracellular region] (Bos taurus)
SCT [extracellular region] (Mus musculus)
SCT [extracellular region] (Rattus norvegicus)
SCT [extracellular region] (Sus scrofa)
Cross References
RefSeq
NP_068739.1
OpenTargets
ENSG00000070031
GeneCards
P09683
PRO
P09683
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8N6Y0 USBP1
0.488
2
UniProt:O14770-4 MEIS2
0.488
2
UniProt:O14964 HGS
2
HGS [phagocytic vesicle lumen]
(R-HSA-9635660)
HGS [cytosol]
(R-HSA-182954)
0.488
2
UniProt:P49639 HOXA1
1
HOXA1 [nucleoplasm]
(R-HSA-5617464)
0.488
2
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