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PTH2R [plasma membrane]
Stable Identifier
R-HSA-420476
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Parathyroid hormone 2 receptor, PTH2R_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
PTH1R,PTH2R:PTH1R,PTH2R ligands [plasma membrane] (Homo sapiens)
PTH1R,PTH2R [plasma membrane] (Homo sapiens)
PTH2R [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
PTH1R,PTH2R:PTH1R,PTH2R ligands [plasma membrane] (Homo sapiens)
PTH1R,PTH2R [plasma membrane] (Homo sapiens)
PTH2R [plasma membrane] (Homo sapiens)
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
PTH1R,PTH2R:PTH1R,PTH2R ligands [plasma membrane] (Homo sapiens)
PTH1R,PTH2R [plasma membrane] (Homo sapiens)
PTH2R [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
PTH1R,PTH2R:PTH1R,PTH2R ligands [plasma membrane] (Homo sapiens)
PTH1R,PTH2R [plasma membrane] (Homo sapiens)
PTH2R [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
PTH1R,PTH2R:PTH1R,PTH2R ligands [plasma membrane] (Homo sapiens)
PTH1R,PTH2R [plasma membrane] (Homo sapiens)
PTH2R [plasma membrane] (Homo sapiens)
GPCRs that activate Gs [plasma membrane] (Homo sapiens)
PTH1R,PTH2R [plasma membrane] (Homo sapiens)
PTH2R [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class B/2 (Secretin family receptors) (Homo sapiens)
Parathyroid hormone receptor can bind parathyroid hormone (Homo sapiens)
PTH1R,PTH2R [plasma membrane] (Homo sapiens)
PTH2R [plasma membrane] (Homo sapiens)
PTH1R,PTH2R:PTH1R,PTH2R ligands [plasma membrane] (Homo sapiens)
PTH1R,PTH2R [plasma membrane] (Homo sapiens)
PTH2R [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P49190 PTH2R
Gene Names
PTH2R, PTHR2
Chain
signal peptide:1-24, chain:25-550
Reference Genes
BioGPS Gene:5746 PTH2R
COSMIC (genes):PTH2R PTH2R
CTD Gene:5746 PTH2R
dbSNP Gene:5746 PTH2R
ENSEMBL:ENSG00000144407 PTH2R
ENSEMBL_homo_sapiens_GENE:ENSG00000144407.10 PTH2R
HGNC:9609 PTH2R
KEGG Gene (Homo sapiens):5746 PTH2R
Monarch:5746 PTH2R
NCBI Gene:5746 PTH2R
OMIM:601469 PTH2R
UCSC:P49190 PTH2R
Reference Transcript
RefSeq:NM_001309516.1 PTH2R
RefSeq:NM_005048.3 PTH2R
Other Identifiers
11732693_a_at
11732694_at
11748069_a_at
16890176
206772_PM_at
206772_at
2525355
2525356
2525357
2525358
2525362
2525363
2525364
2525365
2525366
2525367
2525368
2525369
2525376
2525377
2525378
2525379
2525380
2525381
36388_at
5746
8047910
A_14_P130626
A_23_P380901
GE61526
GO:0004888
GO:0004930
GO:0004991
GO:0005515
GO:0005886
GO:0007165
GO:0007166
GO:0007186
GO:0007188
GO:0008528
GO:0016020
GO:0017046
GO:0023052
GO:0060089
GO:0120162
HMNXSV003023754
ILMN_1729075
PH_hs_0009712
U25128_at
g4826953_3p_at
Participates
as a member of
PTH1R,PTH2R [plasma membrane] (Homo sapiens)
Inferred To
pth2r [plasma membrane]
(Xenopus tropicalis)
Pth2r [plasma membrane]
(Mus musculus)
Pth2r [plasma membrane]
(Rattus norvegicus)
PTH2R [plasma membrane]
(Bos taurus)
PTH2R [plasma membrane]
(Canis familiaris)
PTH2R [plasma membrane]
(Sus scrofa)
zgc:123155 [plasma membrane]
(Danio rerio)
Cross References
RefSeq
NP_001296445.1
,
NP_005039.1
Guide to Pharmacology - Targets
332
OpenTargets
ENSG00000144407
GeneCards
P49190
HPA
ENSG00000144407-PTH2R
Ensembl
ENST00000272847
,
ENSP00000272847
,
ENSG00000144407
PRO
P49190
Pharos - Targets
P49190
Orphanet
24834
PDB
7F16
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