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PTH2(62-100) [extracellular region]
Stable Identifier
R-HSA-420572
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
TIP39, Tuberoinfundibular peptide of 39 residues, PTH2, TIP39_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
PTH1R,PTH2R:PTH1R,PTH2R ligands [plasma membrane] (Homo sapiens)
PTH1R,PTH2R ligands [extracellular region] (Homo sapiens)
PTH2(62-100) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
PTH1R,PTH2R:PTH1R,PTH2R ligands [plasma membrane] (Homo sapiens)
PTH1R,PTH2R ligands [extracellular region] (Homo sapiens)
PTH2(62-100) [extracellular region] (Homo sapiens)
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
PTH1R,PTH2R:PTH1R,PTH2R ligands [plasma membrane] (Homo sapiens)
PTH1R,PTH2R ligands [extracellular region] (Homo sapiens)
PTH2(62-100) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
PTH1R,PTH2R:PTH1R,PTH2R ligands [plasma membrane] (Homo sapiens)
PTH1R,PTH2R ligands [extracellular region] (Homo sapiens)
PTH2(62-100) [extracellular region] (Homo sapiens)
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
PTH1R,PTH2R:PTH1R,PTH2R ligands [plasma membrane] (Homo sapiens)
PTH1R,PTH2R ligands [extracellular region] (Homo sapiens)
PTH2(62-100) [extracellular region] (Homo sapiens)
Ligands of GPCRs that activate Gs [extracellular region] (Homo sapiens)
PTH1R,PTH2R ligands [extracellular region] (Homo sapiens)
PTH2(62-100) [extracellular region] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class B/2 (Secretin family receptors) (Homo sapiens)
Parathyroid hormone receptor can bind parathyroid hormone (Homo sapiens)
PTH1R,PTH2R ligands [extracellular region] (Homo sapiens)
PTH2(62-100) [extracellular region] (Homo sapiens)
PTH1R,PTH2R:PTH1R,PTH2R ligands [plasma membrane] (Homo sapiens)
PTH1R,PTH2R ligands [extracellular region] (Homo sapiens)
PTH2(62-100) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96A98 PTH2
Gene Names
PTH2, TIP39, TIPF39
Chain
signal peptide:1-30, propeptide:31-59, peptide:62-100
Reference Genes
BioGPS Gene:113091 PTH2
COSMIC (genes):PTH2 PTH2
CTD Gene:113091 PTH2
dbSNP Gene:113091 PTH2
ENSEMBL:ENSG00000142538 PTH2
ENSEMBL_homo_sapiens_GENE:ENSG00000142538.2 PTH2
HGNC:30828 PTH2
KEGG Gene (Homo sapiens):113091 PTH2
Monarch:113091 PTH2
NCBI Gene:113091 PTH2
OMIM:608386 PTH2
UCSC:Q96A98 PTH2
Reference Transcript
RefSeq:NM_178449.3 PTH2
Other Identifiers
113091
11734640_at
1555238_PM_at
1555238_at
16874293
3867836
3867837
3867838
3867839
3867840
3867841
8038362
A_23_P357374
GE807962
GO:0005576
GO:0007218
GO:0023052
HMNXSV003019340
Hs2.339845.1.S1_3p_at
ILMN_1673553
PH_hs_0029791
TC19001714.hg
TC19002542.hg
Participates
as a member of
PTH1R,PTH2R ligands [extracellular region] (Homo sapiens)
Inferred To
PTH2 [extracellular region]
(Bos taurus)
PTH2 [extracellular region]
(Canis familiaris)
PTH2 [extracellular region]
(Sus scrofa)
Pth2 [extracellular region]
(Mus musculus)
Pth2 [extracellular region]
(Rattus norvegicus)
pth2 [extracellular region]
(Danio rerio)
Cross References
RefSeq
NP_848544.1
OpenTargets
ENSG00000142538
GeneCards
Q96A98
HPA
ENSG00000142538-PTH2
Ensembl
ENST00000270631
,
ENSP00000270631
,
ENSG00000142538
PRO
Q96A98
Pharos - Targets
Q96A98
PDB
7F16
HMDB Protein
HMDBP08054
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