Nectin/Necl trans heterodimerization

Stable Identifier
R-HSA-420597
Type
Pathway
Species
Homo sapiens
Compartment
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Nectins and Nectin-like molecules (Necls) also undergo trans-heterophilic interactions to interact with other nectin or Necl family members. Besides these trans interactions among nectins and nectin-like family members, trans-homophilic interactions have also been described between nectins or Necls with other immunoglobulin-superfamily members like CD96, CD226 and CRTAM (Sakisaka et al., 2007; Takai et al., 2008). It should be noted that some of these interactions might not exist in epithelial cell-cell contacts but may occur in other cell-cell adhesion systems.

Literature References
PubMed ID Title Journal Year
17942295 The roles of nectins in cell adhesions: cooperation with other cell adhesion molecules and growth factor receptors

Sakisaka, T, Ikeda, W, Ogita, H, Fujita, N, Takai, Y

Curr Opin Cell Biol 2007
Participants
Participant Of
Orthologous Events
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Created