Reactome | CLDN5 [cell junction]

CLDN5 [cell junction]

Stable Identifier

R-HSA-421264

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cell junction

Synonyms

Claudin-5, CLD5_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O00501 CLDN5

Gene Names

CLDN5, AWAL, TMVCF

Chain

chain:1-218

Reference Genes

BioGPS Gene:7122 CLDN5

COSMIC (genes):CLDN5 CLDN5

CTD Gene:7122 CLDN5

dbSNP Gene:7122 CLDN5

ENSEMBL:ENSG00000184113 CLDN5

ENSEMBL_homo_sapiens_GENE:ENSG00000184113.10 CLDN5

HGNC:2047 CLDN5

KEGG Gene (Homo sapiens):7122 CLDN5

Monarch:7122 CLDN5

NCBI Gene:7122 CLDN5

OMIM:602101 CLDN5

UCSC:O00501 CLDN5

Reference Transcript

Other Identifiers

11733299_a_at

204482_PM_at

204482_at

38995_at

3952763

3952764

3952765

3952766

3952767

3952768

7122

8074473

AF000959_at

A_23_P6321

A_24_P79300

A_33_P3285540

GE54025

GO:0003013

GO:0003151

GO:0005198

GO:0005515

GO:0005856

GO:0005886

GO:0005911

GO:0005923

GO:0007043

GO:0007155

GO:0007179

GO:0007612

GO:0008284

GO:0010628

GO:0010629

GO:0016020

GO:0016327

GO:0016328

GO:0016338

GO:0016525

GO:0023052

GO:0030054

GO:0030154

GO:0030336

GO:0030864

GO:0032092

GO:0033270

GO:0034330

GO:0035633

GO:0042552

GO:0042802

GO:0043116

GO:0043220

GO:0043226

GO:0045471

GO:0048856

GO:0048870

GO:0050877

GO:0060021

GO:0060325

GO:0070160

GO:0070161

GO:0070830

GO:0120192

GO:1903142

GO:1903348

GO:1990963

HMNXSV003010395

ILMN_1728197

PH_hs_0029088

g4502878_3p_at

Participates

as an output of

CLDN5 (Claudin-5) gene expression is stimulated by RUNX1 (Homo sapiens)

as a candidate of

Claudin [cell junction] (Homo sapiens)

Other forms of this molecule

CLDN5 [plasma membrane]

Cross References

RefSeq

NP_001124333.1, NP_003268.2

OpenTargets

ENSG00000184113

HPA

ENSG00000184113-CLDN5

GeneCards

O00501

Ensembl

ENST00000618236, ENSG00000184113, ENSP00000480623

PRO

O00501

Pharos - Targets

O00501

Interactors (37)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NZ01 TECR	1	TECR [endoplasmic reticulum membrane] (R-HSA-548663)	0.556	3
UniProt:Q9H0R3 TM222			0.556	3
UniProt:P40313 CTRL			0.556	3
UniProt:O60636 TSN2			0.556	3
UniProt:Q6ZP80 TM182			0.556	3
UniProt:O95183 VAMP5			0.556	3
UniProt:Q969S0 SLC35B4	1	SLC35B4 [Golgi membrane] (R-HSA-742365)	0.556	3
UniProt:Q9P0B6 CC167			0.556	3
UniProt:Q04941 PLP2			0.556	3
UniProt:Q8NBI2 CYAC3			0.556	3
UniProt:Q9NS64 RPRM			0.556	3
UniProt:P29972 AQP1	1	AQP1 [plasma membrane] (R-HSA-431700)	0.556	3
UniProt:Q9Y548 YIPF1			0.556	3
UniProt:Q9BZL3 SMIM3			0.556	3
UniProt:Q9UKR5 ERG28			0.556	3
UniProt:Q8WZ59 TM190			0.556	3
UniProt:Q9BT09 CNPY3	1	CNPY3 [endoplasmic reticulum lumen] (R-HSA-1678932)	0.556	3
UniProt:O43561-2 LAT	2	LAT-2 [plasma membrane] (R-HSA-2396548) p-5Y-LAT-2 [plasma membrane] (R-HSA-2396597)	0.556	3
UniProt:P11686 SFTPC	9	pro-SFTPC P115L [endoplasmic reticulum membrane] (R-HSA-5688352) pro-SFTPC P30L [endoplasmic reticulum membrane] (R-HSA-5688365) pro-SFTPC [endoplasmic reticulum membrane] (R-HSA-5683842) pro-SFTPC [multivesicular body lumen] (R-HSA-5685298) SFTPC [extracellular region] (R-HSA-5683685) SFTPC [clathrin-coated endocytic vesicle] (R-HSA-5686342) SFTPC [lamellar body] (R-HSA-5683717) SFTPC(24-58) [multivesicular body lumen] (R-HSA-5685899) SFTPC(59-197) [multivesicular body lumen] (R-HSA-5685871)	0.556	3
UniProt:Q9Y5Q5 CORIN	1	CORIN(802-1042) [plasma membrane] (R-HSA-5490311)	0.556	3
UniProt:Q01453 PMP22	1	PMP22 [plasma membrane] (R-HSA-9615623)	0.556	3
UniProt:Q08426 EHHADH	2	EHHADH [peroxisomal matrix] (R-HSA-400155) EHHADH [cytosol] (R-HSA-9033147)	0.556	3
UniProt:P02787 TF	6	apoTF [clathrin-coated endocytic vesicle membrane] (R-HSA-8869140) TF [secretory granule lumen] (R-HSA-350704) apoTF [extracellular region] (R-HSA-350754) apoTF [endosome membrane] (R-HSA-917974) p-TF [endoplasmic reticulum lumen] (R-HSA-8957001) TF [endoplasmic reticulum lumen] (R-HSA-8956763)	0.556	3
UniProt:P02724 GYPA	1	GYPA [plasma membrane] (R-HSA-8867204)	0.556	3
UniProt:Q13326 SGCG			0.556	3
UniProt:Q5BJH2-2 TMEM128			0.556	3
UniProt:Q07325 CXCL9	1	CXCL9 [extracellular region] (R-HSA-373856)	0.556	3
UniProt:Q96GM1 PLPPR2	1	LPPR2 [plasma membrane] (R-HSA-6797629)	0.556	3
IntAct:EBI-23343277 CCSB ORF ID			0.556	3
UniProt:Q9NV12 TM140			0.556	3
UniProt:P52803 EFNA5	3	EFNA5 (21-?) N-ter [extracellular region] (R-HSA-3928456) EFNA5 (?-203) C-ter [plasma membrane] (R-HSA-3928431) EFNA5 [plasma membrane] (R-HSA-2682331)	0.556	3
UniProt:Q7Z2K6 ERMP1			0.556	3
UniProt:P30301 MIP	1	MIP [plasma membrane] (R-HSA-432026)	0.556	3
UniProt:Q9P0S9 TM14C			0.556	3
UniProt:Q6UX41-6 Q6UX416			0.556	3
UniProt:Q8TAF8 LHFPL5	1	LHFPL5 [plasma membrane] (R-HSA-9658860)	0.556	3
UniProt:A0PK11 CLRN2			0.556	3

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