Reactome | K+-independent Li+/Ca2+ exchanger transport

K+-independent Li+/Ca2+ exchanger transport

Stable Identifier

R-HSA-425822

Type

Reaction [transition]

Species

Homo sapiens

Compartment

plasma membrane

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

K+-independent Li+/Ca2+ exchanger transport

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

SLC24A6 (NCKX6, NCLX) (Palty R et al, 2004) encodes a protein which can transport Li+ or Na+ in exchange for Ca2+ in an K+-independent manner (Cai X and Lytton J, 2004). Lithium exchange with calcium is shown here.

Literature References

PubMed ID	Title	Journal	Year
14625281	Molecular cloning of a sixth member of the K+-dependent Na+/Ca2+ exchanger gene family, NCKX6 Cai, X, Lytton, J	J Biol Chem	2004
15060069	Lithium-calcium exchange is mediated by a distinct potassium-independent sodium-calcium exchanger Palty, R, Ohana, E, Hershfinkel, M, Volokita, M, Elgazar, V, Beharier, O, Silverman, WF, Argaman, M, Sekler, I	J Biol Chem	2004