Reactome: A Curated Pathway Database

Activation of Protein Kinase C novel isoforms

Stable Identifier
R-HSA-425861
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Activation of the novel Protein Kinase C (nPKC) isoforms (delta, epsilon, eta and theta) requires binding to the membrane lipid diacylglycerol (DAG). nPKC activation is sensitive to DAG concentration.

Literature References
PubMed ID Title Journal Year
19033211 Lipid activation of protein kinases J Lipid Res 2009
  Protein Kinase C 2nd ed   2004
9601053 The extended protein kinase C superfamily Biochem J 1998
Participants
Participant Of
Orthologous Events