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EVL [cytosol]
Stable Identifier
R-HSA-426403
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ena/VASP-like protein, EVL_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
Signaling by ROBO receptors (Homo sapiens)
Ena/VASP proteins bind ROBO1:SLIT2 complex (Homo sapiens)
Ena/VASP Proteins [cytosol] (Homo sapiens)
EVL [cytosol] (Homo sapiens)
SLIT2:ROBO1:Ena/VASP proteins [plasma membrane] (Homo sapiens)
Ena/VASP Proteins [cytosol] (Homo sapiens)
EVL [cytosol] (Homo sapiens)
Recruitment of Profilin by Ena/VASP proteins (Homo sapiens)
SLIT2:ROBO1:Ena/VASP proteins [plasma membrane] (Homo sapiens)
Ena/VASP Proteins [cytosol] (Homo sapiens)
EVL [cytosol] (Homo sapiens)
SLIT2:ROBO1:Ena/VASP:PFN [plasma membrane] (Homo sapiens)
SLIT2:ROBO1:Ena/VASP proteins [plasma membrane] (Homo sapiens)
Ena/VASP Proteins [cytosol] (Homo sapiens)
EVL [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
TCR signaling (Homo sapiens)
Generation of second messenger molecules (Homo sapiens)
p-SLP-76:ADAP binds Ena/VASP (Homo sapiens)
Ena/VASP proteins [cytosol] (Homo sapiens)
EVL [cytosol] (Homo sapiens)
p-SLP-76:ADAP:Ena/VASP [cytosol] (Homo sapiens)
Ena/VASP proteins [cytosol] (Homo sapiens)
EVL [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases Activate Formins (Homo sapiens)
RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 (Homo sapiens)
EVL [cytosol] (Homo sapiens)
EVL [cytosol] (Homo sapiens)
RHOA:GTP:DIAPH1:EVL:Profilin:G-actin [plasma membrane] (Homo sapiens)
EVL [cytosol] (Homo sapiens)
EVL [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UI08 EVL
Gene Names
EVL, RNB6
Chain
chain:1-416
Reference Genes
BioGPS Gene:51466 EVL
COSMIC (genes):EVL EVL
CTD Gene:51466 EVL
dbSNP Gene:51466 EVL
ENSEMBL:ENSG00000196405 EVL
ENSEMBL_homo_sapiens_GENE:ENSG00000196405.13 EVL
HGNC:20234 EVL
KEGG Gene (Homo sapiens):51466 EVL
Monarch:51466 EVL
NCBI Gene:51466 EVL
UCSC:Q9UI08 EVL
Reference Transcript
RefSeq:NM_016337.2 EVL
RefSeq:NM_001330221.1 EVL
Other Identifiers
11727835_a_at
11745874_a_at
11760156_at
217838_PM_s_at
217838_s_at
227232_PM_at
227232_at
3551567
3551568
3551577
3551585
3551586
3551595
3551596
3551600
3551618
3551621
3551623
3551624
3551625
3551628
3551636
3551640
3551641
3551642
3551643
3551644
3551645
3551646
3551647
3551648
3551649
3551650
3551651
3551652
3551653
3551656
3551657
3551658
3551659
3551660
49906_at
51466
57132_at
7976726
A_14_P125305
A_23_P129038
A_23_P140427
A_24_P942648
GE82108
GO:0003779
GO:0005515
GO:0005522
GO:0005737
GO:0005829
GO:0005856
GO:0005925
GO:0007010
GO:0007015
GO:0007166
GO:0007399
GO:0008092
GO:0008154
GO:0009887
GO:0010633
GO:0016020
GO:0017124
GO:0023052
GO:0030027
GO:0030838
GO:0042995
GO:0043226
GO:0048856
GO:0048870
GO:0051289
GO:0051496
GO:0065003
GO:1900028
HMNXSV003038110
Hs.241471.1.A1_3p_at
ILMN_1730622
PH_hs_0012944
PH_hs_0038493
TC14000630.hg
TC14001849.hg
TC14001850.hg
g7706686_3p_s_at
p33773
Participates
as a member of
Ena/VASP Proteins [cytosol] (Homo sapiens)
as a candidate of
Ena/VASP proteins [cytosol] (Homo sapiens)
as a component of
EVL [cytosol] (Homo sapiens)
Inferred To
EVL [cytosol]
(Canis familiaris)
EVL [cytosol]
(Sus scrofa)
ena [cytosol]
(Drosophila melanogaster)
Evl [cytosol]
(Mus musculus)
Evl [cytosol]
(Rattus norvegicus)
unc-34 [cytosol]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_057421.1
,
NP_001317150.1
OpenTargets
ENSG00000196405
GeneCards
Q9UI08
HPA
ENSG00000196405-EVL
Ensembl
ENSP00000437904
,
ENSP00000384720
,
ENSP00000376652
,
ENST00000544450
,
ENSG00000196405
,
ENST00000402714
,
ENST00000392920
PRO
Q9UI08
Pharos - Targets
Q9UI08
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13813 SPTAN1
6
SPTAN1 [cytosol]
(R-HSA-201601)
SPTAN1(1-1185) [cytosol]
(R-HSA-202944)
SPTAN1(1186-2472) [cytosol]
(R-HSA-202964)
SPTAN1 [tertiary granule lumen]
(R-HSA-6800874)
SPTAN1 [extracellular region]
(R-HSA-6806322)
SPTAN1 [specific granule lumen]
(R-HSA-6799533)
0.593
4
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