Reactome | SLC34A3 [plasma membrane]

SLC34A3 [plasma membrane]

Stable Identifier

R-HSA-427665

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Sodium-dependent phosphate transport protein 2C, NPT2C_HUMAN

Locations in the PathwayBrowser

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Transport of small molecules (Homo sapiens)

- SLC-mediated transmembrane transport (Homo sapiens)
  - Transport of inorganic cations/anions and amino acids/oligopeptides (Homo sapiens)
    - Sodium-coupled phosphate cotransporters (Homo sapiens)
      - Type II Na+/Pi cotransporters (Homo sapiens)
        
        SLC34A3 cotransports Pi, 2Na+ (Homo sapiens)
        
        SLC34A3 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q8N130 SLC34A3

Gene Names

SLC34A3, NPT2C, NPTIIC

Chain

chain:1-599

Reference Genes

BioGPS Gene:142680 SLC34A3

COSMIC (genes):SLC34A3 SLC34A3

CTD Gene:142680 SLC34A3

dbSNP Gene:142680 SLC34A3

ENSEMBL:ENSG00000198569 SLC34A3

ENSEMBL_homo_sapiens_GENE:ENSG00000198569.10 SLC34A3

HGNC:20305 SLC34A3

KEGG Gene (Homo sapiens):142680 SLC34A3

Monarch:142680 SLC34A3

NCBI Gene:142680 SLC34A3

OMIM:609826 SLC34A3

UCSC:Q8N130 SLC34A3

Reference Transcript

Other Identifiers

11735668_at

142680

1552510_PM_at

1552510_at

1569926_PM_s_at

1569926_s_at

17091678

4051418

4085366

4096747

8159627

85560_at

A_23_P113682

A_33_P3297468

A_33_P3780983

GE521743

GO:0005215

GO:0005436

GO:0005515

GO:0005886

GO:0005903

GO:0006811

GO:0006814

GO:0006817

GO:0015293

GO:0016020

GO:0016324

GO:0030643

GO:0031526

GO:0031982

GO:0035725

GO:0043226

GO:0044341

GO:0055085

HMNXSV003018288

Hs2.189144.1.S1_3p_at

Hs2.189144.2.S1_3p_s_at

ILMN_1754053

ILMN_1811880

PH_hs_0030163

PH_hs_0033307

TC09002888.hg

Other forms of this molecule

SLC34A3 G191R [plasma membrane]

SLC34A3 G196R [plasma membrane]

SLC34A3 C77Afs*75 [plasma membrane]

SLC34A3 R468W [plasma membrane]

SLC34A3 P303Rfs*40 [plasma membrane]

Inferred To

slc34a3 [plasma membrane] (Xenopus tropicalis)

SLC34A3 [plasma membrane] (Bos taurus)

SLC34A3 [plasma membrane] (Caenorhabditis elegans)

SLC34A3 [plasma membrane] (Canis familiaris)

SLC34A3 [plasma membrane] (Sus scrofa)

Slc34a3 [plasma membrane] (Mus musculus)

Slc34a3 [plasma membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_001170788.1, NP_543153.1, XP_016869781.1, NP_001170787.1

Guide to Pharmacology - Targets

1137

OpenTargets

ENSG00000198569

GeneCards

Q8N130

HPA

ENSG00000198569-SLC34A3

Ensembl

ENSP00000501114, ENST00000538474, ENSP00000442397, ENST00000361134, ENSG00000198569, ENST00000673835, ENSP00000355353

PRO

Q8N130

Pharos - Targets

Q8N130

Orphanet

15321

HMDB Protein

HMDBP03079

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8TED1 GPX8	1	GPX8 [endoplasmic reticulum lumen] (R-HSA-3341303)	0.556	3
UniProt:Q8WY98 TM234			0.556	3
UniProt:Q9NRX6 KISHB			0.556	3
UniProt:P58418 CLRN1			0.556	3

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