Reactome | PAK4 [cytosol]

Stable Identifier

R-HSA-428461

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Serine/threonine-protein kinase PAK 4, PAK4_HUMAN

Locations in the PathwayBrowser

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Developmental Biology (Homo sapiens)

External Reference Information

External Reference

UniProt:O96013 PAK4

Gene Names

PAK4, KIAA1142

Chain

chain:1-591

Reference Genes

COSMIC (genes):PAK4 PAK4

dbSNP Gene:10298 PAK4

ENSEMBL:ENSG00000130669 PAK4

Participates

as a candidate of

as a member of

Inferred To

PAK4 [cytosol] (Bos taurus)

PAK4 [cytosol] (Caenorhabditis elegans)

PAK4 [cytosol] (Canis familiaris)

PAK4 [cytosol] (Dictyostelium discoideum)

PAK4 [cytosol] (Drosophila melanogaster)

PAK4 [cytosol] (Mus musculus)

PAK4 [cytosol] (Rattus norvegicus)

PAK4 [cytosol] (Saccharomyces cerevisiae)

PAK4 [cytosol] (Schizosaccharomyces pombe)

PAK4 [cytosol] (Xenopus tropicalis)

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P63104 YWHAZ	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.916	10
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.88	9
UniProt:P60953 CDC42	3	CDC42 [cytosol] (R-HSA-442630) CDC42 [plasma membrane] (R-HSA-449545) CDC42 [endoplasmic reticulum membrane] (R-HSA-5672086)	0.825	5
UniProt:P62258 YWHAE	1	YWHAE [cytosol] (R-HSA-194368)	0.763	10
UniProt:P31947 SFN	1	SFN [cytosol] (R-HSA-1445105)	0.628	5
UniProt:O00401 WASL	4	p-Y256-WASL [cytosol] (R-HSA-2197672) N-WASP [cytosol] (R-HSA-201873) WASL [plasma membrane] (R-HSA-203010) WASL [endocytic vesicle membrane] (R-HSA-535012)	0.619	8