Reactome | SLC17A5 [lysosomal membrane]

SLC17A5 [lysosomal membrane]

Stable Identifier

R-HSA-428624

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

lysosomal membrane

Synonyms

Sialin, S17A5_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Homo sapiens)
      - Synthesis of substrates in N-glycan biosythesis (Homo sapiens)
        
        Sialic acid metabolism (Homo sapiens)
        
        SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol (Homo sapiens)
        
        SLC17A5 [lysosomal membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9NRA2 SLC17A5

Gene Names

SLC17A5

Chain

chain:1-495

Reference Genes

BioGPS Gene:26503 SLC17A5

COSMIC (genes):SLC17A5 SLC17A5

CTD Gene:26503 SLC17A5

dbSNP Gene:26503 SLC17A5

ENSEMBL:ENSG00000119899 SLC17A5

ENSEMBL_homo_sapiens_GENE:ENSG00000119899.13 SLC17A5

HGNC:10933 SLC17A5

KEGG Gene (Homo sapiens):26503 SLC17A5

Monarch:26503 SLC17A5

NCBI Gene:26503 SLC17A5

OMIM:604322 SLC17A5

UCSC:Q9NRA2 SLC17A5

Reference Transcript

RefSeq:NM_012434.4 SLC17A5

Other Identifiers

11723476_at

11723477_x_at

11752119_x_at

11753191_a_at

11758156_s_at

17020823

221041_PM_s_at

221041_s_at

223441_PM_at

223441_at

26503

2960959

2960960

2960961

2960962

2960963

2960964

2960968

2960970

2960971

2960972

2960977

2960978

2960979

2960980

2960982

2960983

2960994

2960995

2960996

65644_at

8127549

88617_at

A_23_P110896

A_33_P3265270

A_33_P3416321

GE58496

GO:0005215

GO:0005351

GO:0005764

GO:0005765

GO:0005773

GO:0005829

GO:0005886

GO:0006811

GO:0006820

GO:0006865

GO:0009617

GO:0015136

GO:0015293

GO:0015538

GO:0015739

GO:0016020

GO:0016323

GO:0022857

GO:0030672

GO:0031410

GO:0034219

GO:0042874

GO:0042880

GO:0043226

GO:0045202

GO:0055085

GO:1902600

HMNXSV003032940

Hs.117865.1.S2_3p_at

ILMN_1684434

PH_hs_0006462

TC06001876.hg

g6912665_3p_a_at

Other forms of this molecule

SLC17A5 P334R [lysosomal membrane]

SLC17A5 H183R [lysosomal membrane]

SLC17A5 R39C [lysosomal membrane]

SLC17A5 T178Nfs*34 [lysosomal membrane]

SLC17A5 I373Lfs*26 [lysosomal membrane]

Inferred To

SLC17A5 [lysosomal membrane] (Bos taurus)

SLC17A5 [lysosomal membrane] (Canis familiaris)

SLC17A5 [lysosomal membrane] (Dictyostelium discoideum)

SLC17A5 [lysosomal membrane] (Gallus gallus)

SLC17A5 [lysosomal membrane] (Sus scrofa)

Slc17a5 [lysosomal membrane] (Mus musculus)

MFS9 [lysosomal membrane] (Drosophila melanogaster)

slc17a5 [lysosomal membrane] (Xenopus tropicalis)

slc-17.1 [lysosomal membrane] (Caenorhabditis elegans)

zgc:153077 [lysosomal membrane] (Danio rerio)

Cross References

RefSeq

NP_036566.1

Guide to Pharmacology - Targets

1006

OpenTargets

ENSG00000119899

GeneCards

Q9NRA2

HPA

ENSG00000119899-SLC17A5

Ensembl

ENSP00000348019, ENST00000355773, ENSG00000119899

PRO

Q9NRA2

Pharos - Targets

Q9NRA2

Orphanet

15303

HMDB Protein

HMDBP02797

PDB

8DWI