Organic anion transporters

Stable Identifier
R-HSA-428643
Type
Pathway
Species
Homo sapiens
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The SLC17 gene family encode proteins which are organic anion transporters. There are three distinct subfamilies within SLC17; vesicular glutamate transporters (VGLUT1-3 encoded by SLC17A7,6 and 8), type I Na+-coupled phosphate co-transporters (encoded by SLC17A1-4) and a proton-coupled sialic acid co-transporter (encoded by SLC17A5) (Reimer RJ and Edwards RH, 2004).

Two members of the SLC5 gene family encode carboxylate transporters, SMCT1 and SMCT2 (Ganapathy V et al, 2008).

Literature References
PubMed ID Title Journal Year
12811560 Organic anion transport is the primary function of the SLC17/type I phosphate transporter family

Reimer, RJ, Edwards, RH

Pflugers Arch 2004
18446519 Sodium-coupled monocarboxylate transporters in normal tissues and in cancer

Ganapathy, V, Thangaraju, M, Gopal, E, Martin, PM, Itagaki, S, Miyauchi, S, Prasad, PD

AAPS J 2008
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