Reactome: A Curated Pathway Database

Phosphorylation of ROBO1 by ABL kinase

Stable Identifier
R-HSA-428888
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

ABL kinase (ABL1 or ABL2) phosphorylates the tyrosine residue Y1073 of the conserved CC1 motif (PTPYATT) in human ROBO1 (Bashaw et al. 2000).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
protein tyrosine kinase activity of SLIT2:ROBO1:ABL [plasma membrane] SLIT2:ROBO1:ABL [plasma membrane] protein tyrosine kinase activity (0004713)
Orthologous Events