Phosphorylation of ROBO1 by ABL kinase

Stable Identifier
R-HSA-428888
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

ABL kinase (ABL1 or ABL2) phosphorylates the tyrosine residue Y1073 of the conserved CC1 motif (PTPYATT) in human ROBO1 (Bashaw et al. 2000).

Literature References
PubMed ID Title Journal Year
10892742 Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor

Bashaw, GJ, Kidd, T, Murray, D, Pawson, T, Goodman, CS

Cell 2000
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein tyrosine kinase activity of SLIT2:ROBO1:ABL [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed