There will be a maintenance on OICR IT systems starting Friday Dec 15 at 6PM EST until midnight Sunday Dec 17; Reactome will be affected by this downtime

Service under maintenance from Friday Dec 15 at 6PM EST until midnight Sunday Dec 17

ALOX5 is phosphorylated by MAPKAP2

Stable Identifier
R-HSA-429016
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Arachidonate 5-lipoxygenase (ALOX5) catalyzes the first step in leukotriene biosynthesis and has a key role in inflammatory processes. ALOX5 is phosphorylated by MAPKAPK2; MAPKAPK2 is stimulated by arachidonic acid.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of p-T222,S272,T334-MAPKAPK2 [cytosol]
Physical Entity
Activity
Orthologous Events