multiphospho-CERT:PPM1L:VAPA/B + 3 H2O => CERT:PPM1L:VAPA/B + 3 orthophosphate

Stable Identifier
R-HSA-429730
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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PPM1L (protein phosphatase 1-like) catalyzes the dephosphorylation of multiphospho-“CERT” (ceramide transfer protein) that is complexed with it in the endoplasmic reticulum membrane (Saito et al. 2008).

Literature References
PubMed ID Title Journal Year
18165232 Protein phosphatase 2Cepsilon is an endoplasmic reticulum integral membrane protein that dephosphorylates the ceramide transport protein CERT to enhance its association with organelle membranes

Saito, S, Matsui, H, Kawano, M, Kumagai, K, Tomishige, N, Hanada, K, Echigo, S, Tamura, S, Kobayashi, T

J Biol Chem 2008
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine phosphatase activity of multiphospho-CERT:PPM1L:VAPA/B trimer [endoplasmic reticulum membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created